Author

B. Hammock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Zeldin· 2 shared S. H. Hwang· 2 shared A. Asimaki· 1 shared A. Ghetti· 1 shared A. Guha· 1 shared A. Kelly· 1 shared A. T. Ton· 1 shared A. Vik· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

D. Zeldin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy

D. Panigrahy, A. Kelly, W. Wang, J. Yang, S. H. Hwang, M. Gillespie, I. Howard, C. Bueno-Beti, A. Asimaki, V. Penna, K. Lavine, M. Edin, D. Zeldin, B. Hammock, J. Saffitz

This study shows that inhibiting soluble epoxide hydrolase reduces inflammation and myocardial injury in arrhythmogenic cardiomyopathy by increasing pro-resolving lipid mediators.

bioRxiv · Feb 17, 2024Cell Biology

Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis

D. Kim, T. Horimatsu, M. Ogbi, B. Goo, H. Shi, P. Veerapaneni, R. Chouhaita, M. Moses, R. Prasad, T. W. Benson, R. Harb, G. Aboud, H. Sellers, S. Haigh, D. J. R. Fulton, , H. W. Kim

This study shows that disrupting soluble epoxide hydrolase (sEH) in the liver prevents abdominal aortic aneurysm (AAA) formation by reducing inflammatory factors like C3 and SAA.

bioRxiv · Jul 10, 2023 · PreprintPharmacology & Toxicology

Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity

M. T. H. Hrithrik, D.-H. Lee, N. Singh, A. Vik, B. Hammock, Y. Kim

This study investigates the role of EpOMEs and DiHOMEs in insect immune resolution, showing EpOMEs suppress immune responses while DiHOMEs enhance antimicrobial peptide expression, and their dysregulation increases susceptibility to pathogens.

bioRxiv · Jul 7, 2023 · PreprintImmunology

Computational design of peptides to target Nav1.7 channel with high potency and selectivity for the treatment of pain

P. T. Nguyen, H. M. Nguyen, K. M. Wagner, R. Stewart, V. Singh, P. Thapa, Y.-J. Chen, M. W. Lillya, A. T. Ton, R. Kondo, A. Ghetti, M. W. Pennington, B. Hammock, T. N. Griffith, J. T. Sack, , V. Yarov-Yarovoy

The paper designs potent and selective peptide inhibitors of human NaV1.7 channels using Rosetta, with two peptides showing sub-nanomolar IC50 and high selectivity over other sodium channels.

bioRxiv · Jul 21, 2022Biophysics