Cellular protein painting for structural and binding sites analysis via lysine reactivity profiling with o-phthalaldehyde
Z. Zheng, Y. Zeng, K. Lai, B. Liao, P. Li, C. S. H. Tan
This paper introduces RAPID-OPA, a method for intracellular protein labeling and structural analysis, identifying ligand-binding sites and conformational changes in cells.
bioRxiv · Sep 8, 2023 · PreprintCell Biology