Author

A. Rzhetsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Khan· 1 shared A. M. Armando· 1 shared A. P. Mazar· 1 shared A. V. Ugolkov· 1 shared B. F. Cravatt· 1 shared B. Prager· 1 shared B. Schuster· 1 shared C. R. Weber· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Khan

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Author profile →

4 papers

Recent·Most cited

OrganoID: a versatile deep learning platform for tracking and analysis of single-organoid dynamics

J. M. Matthews, B. Schuster, S. S. Kashaf, P. Liu, R. Ben-Yishay, D. Ishay-Ronen, L. Shen, C. Weber, M. Bielski, S. S. Kupfer, M. Bilgic, A. Rzhetsky, S. Tay

OrganoID automatically tracks and analyzes single-organoid dynamics in microscopy images, showing high accuracy in counting, sizing, and morphology analysis across multiple organoid types.

bioRxiv · Jan 13, 2022Bioengineering

Targeting Glioblastoma Signaling and Metabolism with A Re-Purposed Brain-Penetrant Drug

J. Bi, A. Khan, J. Tang, S. Wu, W. Zhang, R. C. Gimple, T. Koga, A. M. Armando, S. Miki, H. Yang, B. Prager, E. J. Curtis, D. A. Wainwright, F. B. Furnari, J. N. Rich, , P. S. Mischel

This study identifies fluoxetine as a potential therapy for glioblastoma by inhibiting SMPD1 and enhancing temozolomide efficacy, with real-world evidence suggesting improved survival.

bioRxiv · Mar 16, 2021Cancer Biology

Mythical and observable trends in human sex ratio at birth

A. Rzhetsky, Y. Long, Q. Chen, H. Larsson

This study examines trends in the human sex ratio at birth using electronic health records, finding no seasonal or temperature effects but associations between pollutants and lower sex ratios.

bioRxiv · Apr 21, 2020 · PreprintPhysiology

Pancreatic adenocarcinoma human organoids share structural and genetic features with primary tumors

I. Romero Calvo, C. R. Weber, M. Ray, M. A. Brown, K. J. Kirby, R. K. Nandi, T. M. Long, S. M. Sparrow, A. V. Ugolkov, W. Qiang, Y. Zhang, T. M. Brunetti, H. L. Kindler, J. P. Segal, A. Rzhetsky, , K. P. White

This study shows that pancreatic cancer organoids closely match primary tumors in molecular features, genetic diversity, and drug responses, suggesting their use in personalized therapy prediction.

bioRxiv · Jun 8, 2018Cancer Biology