Author

C. Schaefer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

M. C. Leake· 4 shared J. Howard· 2 shared A. H. Syeda· 1 shared A. J. Wollman· 1 shared A. Kerrigan· 1 shared A. Noy· 1 shared C. Steele-King· 1 shared D. Conteduca· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiophysics

M. C. Leake

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4 papers

Recent·Most cited

Aggresomes protect mRNA under stress in Escherichia coli

L. Pei, Y. Xian, X. Yan, C. Schaefer, A. H. Syeda, J. Howard, W. Zhang, H. Liao, F. Bai, M. C. Leake, Y. Pu

The paper shows that aggresomes in E. coli store mRNA under stress, aiding rapid recovery by protecting mRNA from degradation and facilitating translation reactivation.

bioRxiv · Apr 27, 2024Biophysics

Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA

J. Shepherd, S. Guilbaud, Z. Zhou, J. Howard, M. Burman, C. Schaefer, A. Kerrigan, C. Steele-King, A. Noy, M. C. Leake

The paper introduces COMBI-Tweez, a tool combining optical and magnetic tweezers with fluorescence microscopy to study the structural dynamics of single chiral biopolymers like DNA under mechanical forces.

bioRxiv · Jan 18, 2024Biophysics

Tween-20 induces the structural remodelling of single lipid vesicles

L. G. Dresser, S. P. Graham, L. M. Miller, C. Schaefer, D. Conteduca, S. Johnson, M. C. Leake, S. D. Quinn

This study investigates how Tween-20 interacts with lipid vesicles, revealing stepwise structural changes even below critical micellar concentration.

bioRxiv · Mar 1, 2022 · PreprintBiophysics

Membraneless organelles formed by liquid-liquid phase separation increase bacterial fitness

X. Jin, J.-E. Lee, C. Schaefer, X. Luo, A. J. Wollman, T. Tian, X. Zhang, X. Chen, Y. Li, M. C. Leake, F. C. Bai

The paper identifies membraneless organelles in bacteria that enhance stress tolerance through liquid-liquid phase separation.

bioRxiv · Jun 24, 2021Biophysics