Author

M. Gardner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. J. Rubin· 2 shared J. B. Wallach· 2 shared K. M. Guinn· 2 shared S. Ehrt· 2 shared S. Wakabayashi· 2 shared A. E. Stark· 1 shared A. Golas· 1 shared A. Orlacchio· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

E. J. Rubin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge Model

X. Wang, H. Su, J. B. Wallach, J. C. Wagner, B. J. Braunecker, M. Gardner, K. M. Guinn, T. Klevorn, K. Lin, Y. J. Liu, Y. Liu, D. Mugahid, M. Rodgers, J. Sixsmith, S. Wakabayashi, , D. Schnappinger

This paper develops an engineered Mycobacterium tuberculosis strain with kill switches for a safe TB human challenge model, showing rapid clearance and low escape rates.

bioRxiv · Nov 19, 2023 · PreprintMicrobiology

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2

H. Mou, B. Quinlan, H. Peng, Y. Guo, S. Peng, L. Zhang, M. Davis-Gardner, M. Gardner, Z. X. Voo, C. C. Bailey, M. Alpert, C. Rader, H. Choe, M. Farzan

bioRxiv · Jun 29, 2020Microbiology

Tagging allows faithful tracing of expression and enhances biochemical detection of Ran Binding Protein 9 in vivo and reveals its interaction with Nucleolin.

S. Soliman, A. E. Stark, M. Gardner, S. W. Harshman, C. C. Breece, F. Amari, A. Orlacchio, M. Chen, A. Tessari, J. A. Martin, R. Visone, M. A. Freitas, K. La Perle, D. Palmieri, V. COPPOLA

The paper generates a novel mouse strain with a tagged RanBP9 protein, enabling reliable detection and revealing its interaction with Nucleolin.

bioRxiv · Dec 3, 2019Bioengineering

Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes

E. O. Johnson, E. LaVerriere, M. Stanley, E. Office, E. Meyer, T. Kawate, J. Gomez, R. E. Audette, N. Bandyopadhyay, N. Betancourt, K. Delano, I. Da Silva, J. Davis, C. Gallo, M. Gardner, , Schnappinge

This study uses a novel chemical-genetics screening strategy to identify new inhibitors of Mycobacterium tuberculosis, revealing novel compound classes targeting previously unexplored bacterial targets.

bioRxiv · Jan 16, 2019Microbiology