Author

D. Cooper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Research Focus:host-pathogen & immune response· 10 Organism:human· 6 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:proteomics· 1

Frequent Co-Authors

J. Zou· 7 shared P.-Y. Shi· 7 shared X. Xie· 7 shared H. Xia· 6 shared K. A. Swanson· 6 shared M. Cutler· 6 shared A. Muik· 5 shared C. Kurhade· 4 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersMicrobiology

J. Zou

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Improved Neutralization of Omicron BA.4/5, BA.4.6, BA.2.75.2, BQ.1.1, and XBB.1 with Bivalent BA.4/5 Vaccine

J. Zou, C. Kurhade, S. Patel, N. Kitchin, K. Tompkins, M. Cutler, D. Cooper, Q. Yang, H. Cai, A. Muik, Y. Zhang, D.-Y. Lee, U. Sahin, A. S. Anderson, W. C. Gruber, , P.-Y. Shi

This study compares the neutralizing antibody responses induced by monovalent and bivalent BA.4/5 vaccines against multiple Omicron sublineages in individuals over 55 years old, finding the bivalent vaccine elicits stronger neutralization.

bioRxiv · Nov 17, 2022 · PreprintMicrobiology

Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by 3 doses of BNT162b2 vaccine or BA.1 infection

C. Kurhade, j. Zou, H. Xia, M. Liu, Q. Yang, M. Cutler, D. Cooper, A. Muik, U. Sahin, K. U. Jansen, P. Ren, X. Xie, K. A. Swanson, P.-Y. Shi

This study evaluates the neutralization of Omicron sublineages and Deltacron by BNT162b2 vaccine or BA.1 infection, finding BA.4/5 shows highest evasion.

bioRxiv · Jun 5, 2022Microbiology

Neutralization of Omicron BA.1, BA.2, and BA.3 SARS-CoV-2 by 3 doses of BNT162b2 vaccine

C. Kurhade, j. Zou, H. Xia, H. Cai, Q. Yang, M. W. Cutler, D. Cooper, A. Muik, K. Jansen, X. Xie, K. Swanson, P.-Y. Shi

This study assesses the neutralization of Omicron sublineages BA.1, BA.2, and BA.3 by BNT162b2 vaccine sera, finding reduced neutralization compared to the original SARS-CoV-2 strain.

bioRxiv · Mar 24, 2022Microbiology

Neutralization of Omicron SARS-CoV-2 by 2 or 3 doses of BNT162b2 vaccine

H. Xia, J. Zou, C. Kurhade, H. Cai, Q. Yang, M. Cutler, D. Cooper, A. Muik, K. U. Jansen, X. Xie, K. A. Swanson, P.-Y. Shi

This study evaluates the neutralization of Omicron SARS-CoV-2 by two or three doses of the BNT162b2 vaccine, showing increased neutralization with three doses but reduced durability over time.

bioRxiv · Jan 21, 2022 · PreprintMicrobiology

BNT162b2-Elicited Neutralization of Delta Plus, Lambda, and Other Variants

J. Liu, Y. Liu, H. Xia, J. Zou, S. Weaver, K. A. Swanson, H. Cai, M. Cutler, D. Cooper, A. Muik, K. U. Jansen, U. Sahin, X. Xie, P. R. Dormitzer, P.-Y. Shi

The paper assesses the neutralization ability of BNT162b2-elicited sera against SARS-CoV-2 variants, finding that all sera neutralize variants to titers of ≥80, indicating vaccine effectiveness against emerging strains.

bioRxiv · Sep 13, 2021 · PreprintMicrobiology

The Immunomodulatory Effects of Social Isolation in Mice are Linked to Temperature Control

A. Hamilton, R. Rizzo, S. Brod, M. Ono, M. Perretti, D. Cooper, F. D'Acquisto

This study shows that social isolation in mice increases resistance to bacterial sepsis, linked to changes in gene expression and cytokine production, which can be reversed by artificial nesting.

bioRxiv · Sep 3, 2021Immunology

Neutralization of spike 69/70 deletion, E484K, and N501Y SARS-CoV-2 by BNT162b2 vaccine-elicited sera

X. Xie, Y. Liu, J. Liu, X. Zhang, J. Zou, C. R. Fontes-Garfias, H. Xia, K. A. Swanson, M. Cutler, D. Cooper, V. D. Menachery, S. Weaver, P. Dormitzer, P.-Y. Shi

The paper evaluates the neutralization effect of BNT162b2 vaccine-elicited sera against SARS-CoV-2 variants with specific spike mutations.

bioRxiv · Jan 27, 2021Microbiology

Neutralization of N501Y mutant SARS-CoV-2 by BNT162b2 vaccine-elicited sera

X. Xie, J. Zou, C. R. Fontes-Garfias, H. Xia, K. A. Swanson, M. Cutler, D. Cooper, V. D. Menachery, S. D. Weaver, P. R. Dormitzer, P.-Y. Shi

The paper assesses the neutralizing activity of BNT162b2 vaccine-elicited sera against N501Y and Y501 SARS-CoV-2 variants, finding equivalent neutralizing titers.

bioRxiv · Jan 7, 2021 · PreprintMicrobiology

Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU

R. Ancar, Y. Li, E. Kindler, D. Cooper, M. Ransom, V. Thiel, S. R. Weiss, J. R. Hesselberth, D. L. Barton

This study identifies the RNA targets of Coronavirus EndoU, showing it cleaves viral RNA at UA and CA sequences to suppress antiviral responses.

bioRxiv · May 20, 2020Microbiology

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque responses

S. Oggero, M. de Gaetano, S. Marcone, M. Barry, T. Montero-Melendez, D. Cooper, L. V. Norling, E. Brennan, C. Godson, M. Perretti

This study shows that EVs from monocyte/platelet aggregates modulate atherosclerotic plaque responses, with Iloprost reducing their pro-inflammatory effects.

bioRxiv · Nov 13, 2019 · PreprintImmunology