Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein C termini
C. L. Frazier, D. Deb, A. M. Weeks
The paper develops an ATP-driven platform for C-terminal protein modification using a bacterial E1-like enzyme, enabling precise bioconjugation with diverse functional groups.
bioRxiv · May 13, 2024 · PreprintBiochemistry