Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming
S. Murphy, S. Rahmy, D. Gan, Y. Zhu, M. Manyak, J. Li, X. Lu, X. Lu
This study shows that combining ketogenic diet and HDAC inhibitors with ICB therapy enhances anti-tumor effects in prostate cancer by modulating epigenetic and immune mechanisms.
bioRxiv · Aug 7, 2023 · PreprintCancer Biology