H. Yi

CoRAL accurately resolves extrachromosomal DNA genomestructures with long-read sequencing

CoRAL improves ecDNA structure reconstruction using long-read sequencing, outperforming short-read methods in simulations and cell-line datasets.

An Evaluation of the Tumor Microenvironment through CALR,IL1R1,IFNB1,and IFNG to Assess Prognosis and Immunotherapy Response in Bladder Cancer Patients

This study evaluates ICD-related genes in bladder cancer to assess prognosis and immunotherapy response, finding higher ICD expression correlates with better survival and response to PD1-targeted therapy.

HLA-Glyco: A large-scale interrogation of the glycosylated immunopeptidome

The paper develops a computational workflow for glyco-immunopeptidomics, identifies glycosylated MHC class II peptides, and provides a resource with over 3,400 HLA class II N-glycopeptides.

Volumetric microscopy of CD9 and CD63 reveals distinct subpopulations and novel structures of extracellular vesicle in situ in triple negative breast cancer cells

Microbiota-stimulated Interleukin-22 regulates brain neurons and protects against stress-induced anxiety

This study identifies IL-22 as a key immune-to-brain signal that reduces stress-induced anxiety by acting on septal neurons.

Effects of Chronic Intermittent Hypoxia and Chronic Sleep Fragmentation on Gut Microbiome, Serum Metabolome, Liver and Adipose Tissue Morphology

This study examines how chronic intermittent hypoxia and chronic sleep fragmentation affect gut microbiota, serum metabolites, and tissue morphology in mice, revealing their impact on lipid metabolism.

LENG8 regulation of mRNA processing, is responsible for the control of mitochondrial activity

This study identifies LENG8 as an mRNA processing factor that regulates mitochondrial activity by controlling mRNA nuclear export and mitochondrial protein expression.

Evolutionary Analysis of Transcriptional Regulation Mediated by Cdx2 in Rodents

This study analyzes evolutionary changes in Cdx2's DNA binding and transcriptional regulation between mice and rats, finding conserved transcriptional output despite divergent DNA binding.

Is Oculudentavis a bird or even archosaur?

This paper reanalyzes CT scan data of Oculudentavis and concludes it is a squamate, not a bird or archosaur, based on morphological evidence.