Author

D. Lawrence

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ashkenazi· 1 shared A. E. Kim· 1 shared A. Ehteda· 1 shared A. Eichler· 1 shared A. Giobbie-Hurder· 1 shared A. Gopalakrishnan· 1 shared A. Khan· 1 shared A. Lee· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Ashkenazi

Author profile →

4 papers

Recent·Most cited

Chromatin remodeling with combined FACT and BET inhibition disrupts oncogenic transcription in Diffuse Midline Glioma

H. Holliday, A. Khan, A. Ehteda, H. Nguyen, S. E. Ross, N. Jayatilleke, A. Gopalakrishnan, E. Wang, Y. Colino Sanguino, D. Kavanagh, X. Guo, J. Liu, D. Lawrence, C. X. Sun, R. Lehmann, , D. S. Ziegler

This study shows that combining FACT and BET inhibition disrupts oncogenic transcription and extends survival in Diffuse Midline Glioma models.

bioRxiv · Jun 6, 2024 · PreprintCancer Biology

Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection

S. Aggarwal, F. C. Walker, J. S. Weagley, B. T. McCune, X. Wu, L. Schreifer, H. Makimaa, D. Lawrence, P. Sridhar, M. T. Baldridge

This study uses barcoded viruses to show that IFN-λ and tuft cell numbers limit persistent murine norovirus infection, with distinct viral populations in intestinal and extraintestinal sites.

bioRxiv · Feb 22, 2024Microbiology

A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

I. Zuazo-Gaztelu, D. Lawrence, I. Oikonomidi, S. Marsters, X. Pechuan-Jorge, C. J. Gaspar, D. Kan, E. Segal, K. Clark, M. Beresini, M.-G. Braun, J. Rudolph, Z. Modrusan, M. Choi, W. Sandoval, , A. Ashkenazi

This study identifies a nonenzymatic role of IRE1 in cancer cell cycle progression and tumor growth, independent of its kinase-RNase activity.

bioRxiv · Nov 22, 2023Cancer Biology

Structural and functional vascular dysfunction within brain metastases is linked to pembrolizumab inefficacy

A. E. Kim, K. W. Lou, A. Giobbie-Hurder, K. Chang, M. Gidwani, K. Hoebel, J. Patel, M. Cleveland, P. Singh, C. Bridge, S. R. Ahmed, B. Bearce, W. Liu, E. Fuster-Garcia, E. Lee, , E. R. Gerstner

This study links structural and functional vascular dysfunction in brain metastases to pembrolizumab resistance by analyzing perfusion MRI data from 44 patients.

bioRxiv · Aug 25, 2023 · PreprintCancer Biology