Author

D. Kireev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bolotokova· 2 shared A. Dong· 2 shared C. H. Arrowsmith· 2 shared E. Gibson· 2 shared I. Chau· 2 shared S. Ackloo· 2 shared A. Allali-Hassani· 1 shared A. Cherkasov· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

A. Bolotokova

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.

S. Ackloo, C. H. Arrowsmith, F. Ban, C. J. Barden, H. Beck, J. Beranek, F. Berenger, A. Bolotokova, G. Bret, M. Breznik, E. Carosati, I. Chau, Y. Chen, A. Cherkasov, D. Della Corte, , Klebe

The paper evaluates computational hit-finding methods for targeting the WDR domain of LRRK2, a Parkinson's disease protein, finding that diverse strategies yielded weakly potent compounds.

bioRxiv · Jul 18, 2024Biochemistry

Graphene Biointerface for Cardiac Arrhythmia Diagnosis and Treatment

Z. Lin, D. Kireev, N. Liu, S. Gupta, J. LaPaino, S. Obaid, Z. Chen, D. Akinwande, I. R. Efimov

This paper introduces a graphene biointerface for in vivo cardiac electrophysiology, demonstrating its use in sensing, stimulation, and treatment of arrhythmias.

bioRxiv · Jun 28, 2022Bioengineering

Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

D. Dilworth, R. P. Hanley, R. Ferreira de Freitas, A. Allali-Hassani, M. Zhou, N. Mehta, M. R. Marunde, S. Ackloo, E. Marcon, F. Li, I. Chau, A. Bolotokova, S. Qin, M. Lei, Y. Liu, , M. Schapira

The paper develops a chemical probe, UNC6934, that targets the PWWP1 domain of NSD2, revealing cooperative control of NSD2 localization through chromatin reader domains.

bioRxiv · Mar 5, 2021 · PreprintCell Biology