Author

A. Maynard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 4 Research Focus:clustering· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2

Frequent Co-Authors

S. Darmanis· 3 shared N. Neff· 2 shared R. Sit· 2 shared W. Tan· 2 shared A. Bizuayehu· 1 shared A. Caccone· 1 shared A. D. Tward· 1 shared A. della Torre· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

S. Darmanis

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Aalbo1200: global genetic differentiation and variability of the mosquito Aedes albopictus

J. E. Crawford, N. Beebe, M. Bonizzoni, B. Caputo, B. H. Carter, C.-H. Chen, L. Cosme, C. M. De Marco, A. della Torre, E. L. Estallo, X. Guo, W.-L. Liu, K. Maringer, J. Mains, A. Maynard, , B. White

This study generates whole genome sequencing data from Aedes albopictus populations to analyze genetic differentiation and variability across tropical and temperate regions.

bioRxiv · Nov 21, 2023 · PreprintEvolutionary Biology

SunCatcher: Clonal Barcoding with qPCR-Based Detection Enables Functional Analysis of Live Cells and Generation of Custom Combinations of Cells for Research and Discovery

Q. Guo, M. Spasic, A. Maynard, G. J. Goreczny, J. F. Olive, A. Bizuayehu, S. S. McAllister

bioRxiv · Oct 13, 2021 · PreprintCancer Biology

Human melanocyte development and melanoma dedifferentiation at single cell resolution

R. L. Belote, D. Le, A. Maynard, U. E. Lang, A. Sinclair, V. Planells-Palop, L. S. Baskin, A. D. Tward, S. Darmanis, R. L. Judson-Torres

This study characterizes human melanocyte development and dedifferentiation using single-cell RNA-sequencing, identifying site-specific subpopulations and transcriptional programs distinct from model systems.

Nature Cell Biology · Sep 2, 2021Peer-reviewedCancer Biology

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

C. P. Ponting, J. Baran-Gale, M. D. Morgan, S. Maio, F. Dhalla, I. Calvo-Asensio, M. Deadman, A. E. Handel, A. Maynard, S. Chen, F. Green, R. Sit, N. Neff, S. Darmanis, W. Tan, , G. A. Holländer

This study investigates how ageing affects mouse thymus function, revealing that progenitor cell differentiation is disrupted, leading to impaired T cell selection and self-antigen representation.

bioRxiv · Mar 2, 2020Immunology

Heterogeneity and targeted therapy-induced adaptations in lung cancer revealed by longitudinal single-cell RNA sequencing

A. Maynard, C. E. McCoach, J. K. Rotow, L. Harris, F. Haderk, L. D. Kerr, E. A. Yu, E. L. Schenk, W. Tan, A. Zee, M. Tan, P. Gui, T. Lea, W. Wu, A. Urisman, , T. G. Bivona

This study uses longitudinal single-cell RNA sequencing to reveal therapy-induced adaptations in lung cancer, identifying cell state transitions and pathways associated with treatment response and resistance.

bioRxiv · Dec 8, 2019 · PreprintCancer Biology

The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting

K. L. Dunlevy, V. Medvedeva, J. E. Wilson, M. Hoque, T. Pellegrin, A. Maynard, M. M. Kremp, J. S. Wasserman, A. Poleshko, R. A. Katz

This study identifies a modular nuclear lamina binding domain in PRR14 that mediates heterochromatin anchoring and is regulated by phosphorylation and a PP2A phosphatase site.

bioRxiv · Oct 8, 2019Cell Biology