Author

E. Hoffman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Cohen-Gadol· 1 shared A. Gao· 1 shared A. Kumar· 1 shared A. Majumdar· 1 shared A. Sarkozy· 1 shared A. Shah· 1 shared C. C. Martin· 1 shared C. Espy· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. Cohen-Gadol

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enabling non-viral DNA delivery using lipid nanoparticles co-loaded with endogenous anti-inflammatory lipids

M. N. Patel, S. Tiwari, Y. Wang, S. O'Neill, J. Wu, S. Omo-Lamai, C. Espy, L. S. Chase, A. Majumdar, E. Hoffman, A. Shah, A. Sarkozy, J. Katzen, N. Pardi, J. S. Brenner

This study develops lipid nanoparticles co-loaded with anti-inflammatory lipids to reduce inflammation from DNA delivery, enabling prolonged transgene expression.

bioRxiv · Jun 11, 2024Bioengineering

Insect hormone PTTH regulates lifespan through temporal and spatial activation of NF-κB signaling during metamorphosis

P. Kang, P. Liu, J. Kim, A. Kumar, M. Bolton, W. A. Murzyn, Z. J. Anderson, L. N. Frank, N. Kavlock, E. Hoffman, C. C. Martin, M. K. Dorneich-Hayes, T. Miao, M. Shimell, W. Chen, , H. Bai

This study shows that PTTH loss-of-function in Drosophila extends lifespan by repressing NF-κB signaling in oenocytes during metamorphosis.

bioRxiv · Sep 30, 2023 · PreprintPhysiology

Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas

J. Z. Wang, V. Patil, J. Liu, H. Dogan, F. Behling, M. Skardelly, M. Tatagiba, E. Hoffman, S. Bunda, R. Yakubov, R. Kaloti, S. Brandner, A. Gao, A. Cohen-Gadol, J. Barnholtz-Sloan, , International Consortium on Meningiomas (ICOM)

This study investigates the relationship between CDKN2A mRNA expression and clinical outcomes in meningiomas, finding that high expression is associated with poorer progression-free survival and more aggressive tumor characteristics.

Acta Neuropathologica · Jul 1, 2023Peer-reviewedCancer Biology