Author

E. Ortlund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Chandele· 1 shared A. Folick· 1 shared A. Patel· 1 shared A. S. Neish· 1 shared A. Sharma· 1 shared C. Chakravarthy· 1 shared C. D. Okafor· 1 shared C. W. Davis· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Chandele

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits

S. Mays, D. Hercules, e. Ortlund, C. D. Okafor

This study identifies distinct allosteric signaling circuits used by active and inactive ligands to communicate with the AFS of LRH-1, revealing new therapeutic targets and mechanisms of coregulator signaling.

bioRxiv · Jan 27, 2023Biochemistry

Structural insights for neutralization of BA.1 and BA.2 Omicron variants by a broadly neutralizing SARS-CoV-2 antibody

S. Kumar, A. Patel, L. Lai, C. Chakravarthy, R. Valanparambil, M. E. Davis-Gardner, V. V. Edara, S. Linderman, E. S. Reddy, K. Gottimukkala, K. Nayak, P. Bajpai, V. Singh, F. Frank, N. Cheedarla, , A. Chandele

This paper identifies and structurally analyzes an antibody that neutralizes SARS-CoV-2 BA.1 and BA.2 variants, revealing its unique epitope and mechanism of action.

bioRxiv · May 13, 2022Immunology

Lysosome Lipid Signaling from the Periphery to Neurons Regulates Longevity

M. Savini, J. D. Duffy, A. Folick, Y.-T. Lee, P.-W. Hu, I. Neve, F. Jin, Q. Zhang, M. Tillman, Y. Ye, W. Mair, J. Wang, L. Han, E. Ortlund, M. C. Wang

This study identifies a lysosomal lipid signaling pathway from fat to neurons in C. elegans that promotes longevity by regulating neuropeptide signaling.

bioRxiv · Jun 10, 2021 · PreprintCell Biology