Author

P. A. Mudd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. A. O'Halloran· 3 shared R. M. Presti· 3 shared T. Lei· 3 shared A. E. Gelman· 2 shared A. Haile· 2 shared A. J. Schmitz· 2 shared A. M. Rauseo· 2 shared C. W. Goss· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

J. A. O'Halloran

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Structural Mapping of Polyclonal IgG Responses to HA After Influenza Virus Vaccination or Infection

A. N. Leon, A. J. Rodriguez, S. T. Richey, A. Torrents de la Pena, R. M. Wolters, A. M. Jackson, K. Webb, C. B. Creech, S. Yoder, P. A. Mudd, J. E. Crowe, J. Han, A. B. Ward

The paper uses nsEMPEM to analyze polyclonal IgG responses to HA in vaccinated and infected individuals, showing differences in epitope targeting between H1 and H3 subtypes.

bioRxiv · Jul 8, 2024Immunology

The salivary and nasopharyngeal microbiomes are associated with SARS-CoV-2 infection and disease severity

J. G. Kim, A. Zhang, A. M. Rauseo, C. W. Goss, P. A. Mudd, J. O'Halloran, L. Wang

This study examines the association between salivary and nasopharyngeal microbiomes and SARS-CoV-2 infection severity, finding specific bacterial taxa linked to disease outcomes.

bioRxiv · May 31, 2022Microbiology

Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination

W. Kim, J. Q. Zhou, A. J. Sturtz, S. C. Horvath, A. J. Schmitz, T. Lei, E. Kalaidina, M. Thapa, W. B. Al Soussi, A. Haile, M. K. Klebert, T. Suessen, L. Parra-Rodriguez, P. A. Mudd, W. D. Middleton, , A. H. Ellebedy

This study tracks the maturation of B cell responses to SARS-CoV-2 vaccination, showing that memory B cells and bone marrow plasma cells accumulate somatic hypermutations over time, enhancing antibody avidity.

bioRxiv · Oct 31, 2021 · PreprintImmunology

SARS-CoV-2 mRNA vaccination elicits robust and persistent T follicular helper cell response in humans

P. A. Mudd, A. A. Minervina, M. V. Pogorelyy, J. S. Turner, W. Kim, E. Kalaidina, J. Petersen, A. J. Schmitz, T. Lei, A. Haile, A. M. Kirk, R. C. Mettelman, J. C. Crawford, T. H. O. Nguyen, L. C. Rowntree, , A. Ellebedy

This study shows that SARS-CoV-2 mRNA vaccination leads to strong and long-lasting T follicular helper cell responses in humans.

bioRxiv · Sep 8, 2021Immunology

Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.

L. Ma, S. K. Sahu, M. Cano, V. Kuppuswamy, J. Bajwa, J. McPhatter, A. B. Pine, M. M. Meizlish, G. Goshua, C. H. Chang, H. Zhang, C. Price, P. Bahel, H. M. Rinder, T. Lei, , H. S. Kulkarni

The paper shows that complement activation is higher in severe SARS-CoV-2 infection compared to influenza and non-COVID respiratory failure, with the alternative pathway linked to worse outcomes.

bioRxiv · Feb 22, 2021Immunology

Circulating Mitochondrial DNA is an Early Indicator of Severe Illness and Mortality from COVID-19

D. Scozzi, M. Cano, L. MA, D. Zhou, J. H. Zhu, J. A. O'Halloran, C. Goss, A. Rauseo, Z. Liu, V. Peritore, M. Rocco, A. Ricci, R. Amodeo, L. Aimati, M. Ibrahim, , A. E. Gelman

This study shows that high levels of circulating mitochondrial DNA predict severe illness and mortality in COVID-19 patients.

bioRxiv · Jul 30, 2020Immunology