Author

T. Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. B. A. Laranjeira· 2 shared L. Yu· 2 shared S. Oh· 2 shared A. DAlessandro· 1 shared A. Liu· 1 shared A. Wang· 1 shared A. Z. Wang· 1 shared A. Zhang· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

A. B. A. Laranjeira

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Author profile →

5 papers

Recent·Most cited

Multiomic Profiling Reveals Metabolic Alterations Mediating Aberrant Platelet Activity and Inflammation in Myeloproliferative Neoplasms

F. He, A. B. A. Laranjeira, t. kong, A. Liu, K. Bark, N. M. Lasky, D. A. C. Fisher, M. J. Cox, M. Fulbright, L. A. Heck, L. Yu, S. M. Sykes, A. DAlessandro, J. Di Paola, S. Oh

This study identifies metabolic alterations in MPN platelets, showing that alpha-ketoglutarate supplementation reduces hyperreactivity and inflammation.

Journal of Clinical Investigation · Feb 1, 2024Peer-reviewedCancer Biology

A telomere-to-telomere genome assembly of Zhonghuang 13, a widely-grown soybean variety from the original center of Glycine max

A. Zhang, T. Kong, B. Sun, S. Qiu, J. Guo, S. Ruan, Y. Guo, J. Guo, Z. Zhang, Y. Liu, Z. Hu, T. Jiang, Y. Liu, S. Cao, S. Sun, , Y. Wang

This paper presents the first telomere-to-telomere genome assembly of the soybean cultivar Zhonghuang 13, resolving gaps and identifying novel genes and structural variations.

bioRxiv · Sep 27, 2023Plant Biology

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression

T. Kong, A. B. A. Laranjeira, K. Yang, D. Fisher, L. Yu, A. Z. Wang, M. Ruzinova, J. Fowles, M. Allen, H. Celik, G. Challen, S. Huang, S. Oh

This study identifies DUSP6 as a driver of leukemic progression and resistance to JAK2 inhibition in MPNs, highlighting the DUSP6-RSK1 axis as a therapeutic target.

Nature Cancer · Dec 29, 2022Peer-reviewedCancer Biology

Exosome-mediated apoptosis pathway during WSSV infection in crustacean mud crab

Y. Gong, T. Kong, X. Ren, J. Chen, S. Lin, Y. Zhang, S. Li

The paper investigates exosome-mediated apoptosis during WSSV infection in mud crabs, identifying miR-137 and miR-7847 as negative regulators of apoptosis by targeting AIF.

bioRxiv · Feb 3, 2020Immunology

Delving below the species level to characterize the ecological diversity within the global virome: An exploration of West Nile Virus

T. Kong, K. Mei, A. Wang, D. Krizanc, F. M. Cohan

The paper demonstrates a method to discover ecological diversity within a virus species using genome-based phylogeny and ecotype simulation, showing heterogeneity in host associations among West Nile Virus ecotypes.

bioRxiv · Dec 12, 2019 · PreprintMicrobiology