Author

I. Dardani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

A. Raj· 4 shared A. Kaur· 2 shared A. T. Weeraratna· 2 shared K. A. Alexander· 2 shared M. Herlyn· 2 shared Y. Goyal· 2 shared A. J. Cote· 1 shared A. L. Good· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

A. Raj

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer

K. A. Alexander, R. Yu, N. Skuli, N. J. Coffey, S. Nguyen, C. Faunce, H. Huang, I. Dardani, A. L. Good, J. Lim, C. Li, N. Biddle, E. F. Joyce, A. Raj, D. Lee, , S. L. Berger

This study shows nuclear speckles vary in cancer, correlate with survival in kidney cancer, and are regulated by HIF-2 through speckle targeting motifs.

bioRxiv · Sep 14, 2023 · PreprintCancer Biology

Metastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation

A. Kaur, L. Cuenca, K. Kiani, G. Busch, D. Fingerman, M. C. Dunagin, J. Li, I. Dardani, E. M. Sanford, J. Pemberton, Y. Goyal, A. T. Weeraratna, M. Herlyn, A. Raj

The paper identifies a rare invasive subpopulation of melanoma cells that drives metastasis, independent of environment, through non-genetic gene expression fluctuations.

bioRxiv · Apr 17, 2022 · PreprintCancer Biology

clampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

I. Dardani, B. L. Emert, Y. Goyal, C. L. Jiang, A. Kaur, J. Lee, S. H. Rouhanifard, G. M. Alicea, M. E. Fane, M. Xiao, M. Herlyn, A. T. Weeraratna, A. Raj

clampFISH 2.0 enables rapid, scalable detection of multiple RNA species in single cells and tissue sections by improving signal amplification and reducing time and cost.

bioRxiv · Mar 16, 2022Bioengineering

Post-transcriptional splicing can occur in a slow-moving zone around the gene

A. J. Cote, A. O'Farrell, I. Dardani, M. Dunagin, C. J. Cote, Y. Wan, S. Bayatpour, H. L. Drexler, K. A. Alexander, F. Chen, A. T. Wassie, R. Patel, K. Pham, E. S. Boyden, S. Berger, , A. Raj

The paper uses imaging techniques to show that splicing occurs in a slow-moving zone near the transcription site, suggesting a model where splicing is post-transcriptional but occurs close to transcription.

bioRxiv · Apr 6, 2020Cell Biology