Author

J. Amrute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1

Frequent Co-Authors

A. Bredemeyer· 2 shared C.-Y. Lin· 2 shared K. Lavine· 2 shared A. Koenig· 1 shared A. Parks· 1 shared A. Villanueva· 1 shared B. Kopecky· 1 shared C. Frye· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Bredemeyer

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Expansion of Disease Specific Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis

P. Ma, J. Liu, J. Qin, L. Lai, G. S. Heo, H. Luehmann, D. Sultan, A. Bredemeyer, G. Bajpai, G. Feng, J. Jimenez, A. Parks, J. Amrute, A. Villanueva, Y. Liu, , K. Lavine

This study identifies an inflammatory macrophage population expanded in ICI myocarditis, driven by IFN-γ signaling and T-cell interactions, suggesting IFN-γ blockade as a potential therapeutic strategy.

bioRxiv · Apr 28, 2023 · PreprintImmunology

Donor Macrophages Modulate Rejection after Heart Transplantation

B. Kopecky, H. Dun, J. Amrute, C.-Y. Lin, A. Bredemeyer, Y. Terada, P. Bayguinov, A. Koenig, C. Frye, J. Fitzpatrick, D. Kreisel, K. Lavine

This study identifies donor CCR2+ macrophages as key drivers of heart transplant rejection and shows that inhibiting MYD88 signaling in these cells extends graft survival.

Circulation · Aug 23, 2022Peer-reviewedImmunology