Author

H. Dun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

D. Kreisel· 4 shared B. W. Wong· 3 shared K. Lavine· 2 shared L. Ye· 2 shared W. Li· 2 shared Y. Terada· 2 shared Y. Zhu· 2 shared A. Arthanarisami· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersImmunology

D. Kreisel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hypoxia Sensing in Resident Cardiac Macrophages Regulates Monocyte Fate Specification following Ischemic Heart Injury

F. F. Kadyrov, A. L. Koenig, J. M. Amrute, H. Dun, W. Li, C. J. Weinheimer, J. M. Nigro, A. Kovacs, A. L. Bredemeyer, L. Lai, B. J. Kopecky, V. Penna, D. Kreisel, K. J. Lavine

This study shows that hypoxia sensing in cardiac macrophages influences monocyte differentiation into inflammatory states after heart injury.

bioRxiv · Aug 4, 2022 · PreprintImmunology

Targeting fatty acid beta-oxidation impairs monocyte differentiation and prolongs heart allograft survival

Y. Zhu, H. Dun, L. Ye, Y. Terada, L. Shriver, G. J. Patti, D. Kreisel, A. E. Gelman, B. W. Wong

This study shows that inhibiting fatty acid beta-oxidation impairs monocyte differentiation and improves heart allograft survival by reducing immune cell infiltration.

bioRxiv · Feb 9, 2022Immunology

Donor Macrophages Modulate Rejection after Heart Transplantation

B. Kopecky, H. Dun, J. Amrute, C.-Y. Lin, A. Bredemeyer, Y. Terada, P. Bayguinov, A. Koenig, C. Frye, J. Fitzpatrick, D. Kreisel, K. Lavine

This study identifies donor CCR2+ macrophages as key drivers of heart transplant rejection and shows that inhibiting MYD88 signaling in these cells extends graft survival.

bioRxiv · Sep 17, 2021Immunology

Circulating osteopontin released by injured kidneys causes pulmonary inflammation and edema

F. Z. Khamissi, L. Ning, E. Kefaloyianni, H. Dun, A. Arthanarisami, A. Keller, J. J. Atkinson, W. Li, B. W. Wong, S. Dietmann, K. Lavine, D. Kreisel, A. Herrlich

This study identifies osteopontin (OPN) released by injured kidneys as a mediator of acute lung injury, showing its role in causing pulmonary inflammation and edema.

bioRxiv · Jul 20, 2021 · PreprintCell Biology

Combined abdominal heterotopic heart and aorta transplant model in mice

H. Dun, L. Ye, Y. Zhu, B. W. Wong

This paper develops a combined abdominal heart and aorta transplant model in mice to study allograft vasculopathy and immunosuppressive strategies.

bioRxiv · Mar 6, 2020Pathology