Author

J. Ly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Ashkenazi· 1 shared A. Bankston· 1 shared A. Gogineni· 1 shared A. Heidersbach· 1 shared A. Le Thomas· 1 shared A. Ralston· 1 shared B. Haley· 1 shared C. S. Blengini· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Ashkenazi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Identification and characterization of a human MORC2 DNA binding region that is required for gene silencing

N. L. Fendler, J. Ly, L. Welp, H. Urlaub, S. M. Vos

This study identifies a DNA binding region in MORC2 that is essential for gene silencing and shows that phosphorylation affects its DNA affinity and nuclear localization.

bioRxiv · Jun 5, 2024Biochemistry

A conserved germline-specific Dsn1 alternative splice isoform supports oocyte and embryo development

J. Ly, C. S. Blengini, S. Cady, K. Schindler, I. M. Cheeseman

This study identifies a germline-specific DSN1 splice isoform essential for oocyte maturation and early embryonic development in mammals.

bioRxiv · Apr 17, 2024Cell Biology

CD8+ T cell response promotes viral clearance and reduces chances of severe testicular damage in mouse models of long-term Zika virus infection of the testes.

R. Kroon Campos, Y. Liang, S. R. Azar, J. Ly, V. Neves Camargos, E. E. Hager-Soto, E. Eyzaguirre, J. Sun, S. L. Rossi

This study shows CD8+ T cells reduce severe testicular damage in mice with long-term Zika virus infection by promoting viral clearance.

bioRxiv · Jan 22, 2024 · PreprintMicrobiology

Development and Outcomes of an International Certificate Program in Science Policy and Advocacy for STEM PhD Students and Postdocs

A. Bankston, A. Ralston, J. Ly, H. Singh

The paper describes an international certificate program in science policy and advocacy for STEM PhD students and postdocs, showing it helped participants transition into policy roles and careers.

bioRxiv · Nov 26, 2023 · PreprintScientific Communication & Education

Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma

J. M. Harnoss, A. Le Thomas, S. A. Marsters, D. A. Lawrence, M. Lu, Y.-C. A. Chen, J. Qing, K. Totpal, D. Kan, E. Segal, H. Ackerly Wallweber, W. Wang, K. Clark, S. Kaufman, M. Beresini, , A. Ashkenazi

This study shows that disrupting IRE1α's kinase domain reduces multiple myeloma tumor growth and enhances treatment efficacy, suggesting it as a therapeutic target.

bioRxiv · Dec 14, 2018 · PreprintCancer Biology