HMGN5 escorts oncogenic STAT3 signaling by regulating chromatin landscape in tumorigenesis of breast cancer
J. Mou, M. Huang, F. Wang, X. Xu, H. Xie, H. Lu, M. Li, Y. Li, W. Kong, J. Chen, Y. Xiao, Y. Chen, C. Wang, J. Ren
This study identifies HMGN5 as a novel epigenetic target in breast cancer by showing it promotes tumorigenesis through STAT3-mediated chromatin regulation and suggests siRNA-based therapy.
bioRxiv · Jan 4, 2022Cancer Biology