Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy
Y. Zhang, D. Karagiannis, H. Liu, M. Lin, Y. Fang, M. Jiang, X. Chen, S. Suresh, H. Huang, J. She, F. Shi, P. Yang, W. El-Rifai, A. Zaika, A. E. Oro, , J. Que
This study shows that p63 regulates the balance between squamous and neuroendocrine cell fates in esophageal development and cancer by modulating epigenetic mechanisms.
bioRxiv · Sep 9, 2023Cell Biology