Condensates of synaptic vesicles and synapsin are molecular beacons for actin sequestering and polymerization
A. Chhabra, C. Hoffmann, G. Aguilar Perez, A. Korobeinikov, J. Rentsch, N. Huempfer, L. Kokwaro, L. Gnidovec, A. Petrovic, J. Wallace, J. V. Tromm, R.-V. Cristina, E. Johnson, B. Rankovic, E. Perego, , D. Milovanovic
The paper investigates how synapsin-SV condensates organize presynaptic actin through LLPS, revealing their role in SV clustering and actin polymerization in lamprey and mammalian synapses.
bioRxiv · Jul 19, 2024 · PreprintCell Biology