Author

J.-Y. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 2 Physiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Q. Wang· 2 shared X.-Y. Ge· 2 shared Y. Qiu· 2 shared Z.-J. Zhou· 2 shared A. Scaloni· 1 shared A. Svanbergsson· 1 shared A. Wu· 1 shared B. Colella· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Q. Wang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen

W.-p. Yang, M.-q. Li, J. Ding, J.-y. Li, G. Wu, B. Liu, Y.-q. Gao, G. Wang, Q.-q. Luo

This study shows that high-altitude hypoxia induces splenic macrophage ferroptosis, reducing erythrophagocytosis and contributing to high-altitude polycythemia.

bioRxiv · Mar 23, 2023Physiology

Key mutations on spike protein altering ACE2 receptor utilization and potentially expanding host range of emerging SARS-CoV-2 variants

Q. Wang, S.-B. Ye, Z.-J. Zhou, J.-Y. Li, J.-Z. Lv, B. Hu, S. Yuan, Y. Qiu, X.-Y. Ge

This study identifies key spike protein mutations in SARS-CoV-2 variants that enhance ACE2 receptor utilization across multiple animal species, potentially increasing host range and spillover risk.

bioRxiv · Apr 11, 2022Microbiology

Genomic evidence for divergent co-infections of SARS-CoV-2 lineages

H.-Y. Zhou, Y.-X. Cheng, L. Xu, J.-Y. Li, C.-Y. Tao, C.-Y. Ji, N. Han, R. Yang, Y. Li, A. Wu

This study identifies co-infection events of SARS-CoV-2 lineages in genomic data, finding 53 events across 29,993 samples, including one triple lineage infection, and notes an increasing trend with viral diversity.

bioRxiv · Sep 3, 2021 · PreprintMicrobiology

The bacterial amyloids phenol soluble modulins from Staphylococcus aureus catalyze alpha-synuclein aggregation

C. Haikal, L. Ortigosa, K. Bernfur, A. Svanbergsson, S. Linse, J.-Y. Li

This study shows that Staphylococcus aureus PSM peptides catalyze alpha-synuclein aggregation, potentially linking the microbiome to Parkinson's disease pathology.

bioRxiv · Mar 10, 2021Biochemistry

Receptor utilization of angiotensin converting enzyme 2 (ACE2) indicates a narrower host range of SARS-CoV-2 than that of SARS-CoV

Y. Qiu, Q. Wang, J.-Y. Li, C.-H. Liao, Z.-J. Zhou, X.-Y. Ge

This study compares the receptor utilization of SARS-CoV and SARS-CoV-2 using ACE2s from 20 animals, finding SARS-CoV-2 uses fewer ACE2s, suggesting a narrower host range.

Transboundary and Emerging Diseases · Sep 5, 2020Peer-reviewedMicrobiology

Low-protein/high-carbohydrate diet induces AMPK-dependent canonical and non-canonical thermogenic response in subcutaneous adipose tissue

K. Aquilano, F. Sciarretta, R. Turchi, B.-H. Li, M. Rosina, V. Ceci, G. Guidobaldi, S. Arena, C. D'Ambrosio, M. Audano, I. Salvatori, B. Colella, R. Faraonio, C. Panebianco, V. Pazienza, , D. Lettieri-Barbato

This study shows that a low-protein/high-carbohydrate diet activates AMPK-dependent thermogenic pathways in subcutaneous adipose tissue, enhancing energy dissipation and metabolic health.

bioRxiv · Feb 26, 2020Physiology

Integrative model to coordinate the oligomerization and aggregation mechanisms of CCL5

Y.-C. Chen, S.-P. Chen, J.-Y. Li, P.-C. Chen, Y.-Z. Lee, K.-M. Li, R. Zarivach, Y.-J. Sun, S.-C. Sue

This study identifies two dimer-dimer interactions and one aggregation mechanism in CCL5 oligomerization using NMR and biophysical analyses.

bioRxiv · Sep 3, 2019Biochemistry