L. Parida

AutoXAI4Omics: an Automated Explainable AI tool for Omics and tabular data

AutoXAI4Omics automates and explains ML pipelines for omics and tabular data, enabling interpretable insights for biomarker discovery and phenotype prediction.

Latent human herpesvirus 6 is reactivated in chimeric antigen receptor T cells

The paper identifies HHV-6 reactivation in CAR T cells using single-cell sequencing and links it to clinical neurotoxicity observed in patients.

Bacterial metatranscriptomes in wastewater can differentiate virally infected human populations

The paper shows that bacterial metatranscriptomes in wastewater can distinguish SARS-CoV-2 infected from uninfected human populations without directly detecting viral transcripts.

Multi-omics profiling of Earth's biomes reveals patterns of diversity and co-occurrence in microbial and metabolite composition across environments

The paper performs a multi-omics meta-analysis of microbial and metabolite data from diverse environments, revealing patterns of diversity and co-occurrence across biomes.

Integrative molecular and clinical profiling of acral melanoma identifies LZTR1 as a key tumor promoter and therapeutic target

Lesion Shedding Model: unraveling site-specific contributions to ctDNA.

The paper introduces the Lesion Shedding Model (LSM) to rank tumor lesions by their ctDNA shedding levels and demonstrates its accuracy in identifying top shedding lesions in cancer patients.

Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity

This study shows that commensal bacteria modify heparan sulfate, reducing SARS-CoV-2 spike protein binding and that this bacterial presence decreases with age, increasing COVID-19 susceptibility.

Monitoring the microbiome for food safety and quality using deep shotgun sequencing

The paper uses deep shotgun sequencing to analyze food microbiomes, identifying microbial genera and observing shifts related to ingredient composition, but finds limited correlation between RNA sequencing and Salmonella growth.