A. Evans

AutoXAI4Omics: an Automated Explainable AI tool for Omics and tabular data

AutoXAI4Omics automates and explains ML pipelines for omics and tabular data, enabling interpretable insights for biomarker discovery and phenotype prediction.

Mimicking an in cellulo environment for enzyme-free paper-based nucleic acid tests at the point of care

This paper develops an enzyme-free nucleic acid test using hybridization chain reaction and paper-based filtration to detect sub pM DNA levels, mimicking in cellulo conditions for point-of-care diagnostics.

Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

The paper determines the structure of the SIT1 proline transporter complexed with ACE2 using cryo-EM, revealing substrate specificity and structural changes related to transport and a disease-causing mutation.

Global mosquito virome profiling and mosquito spatial diffusion pathways revealed by marker-viruses

The paper profiles global mosquito viromes across species, locations, and climates, identifies core-viruses, and links viral diversity to ecological factors and mosquito movement.

Spatial structure formation by RsmE-regulated extracellular secretions in Pseudomonas fluorescens Pf0-1

This study shows that RsmE-regulated secretions in Pseudomonas fluorescens Pf0-1 create and protect low-density spaces, with biosurfactant gacamide A defining genotypic boundaries.

Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in Drosophila

This study shows that aged Drosophila have impaired disease tolerance to RNA virus infection, marked by stronger transcriptional responses and altered gene regulation related to apoptosis and mitochondrial function.

Evaluation of cerebellar function scores in relation to cerebellar axonal loss in multiple sclerosis

This study evaluates cerebellar function scores in relation to axonal loss in multiple sclerosis using diffusion MRI and clinical assessments.

Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2

This study evaluates the efficacy of CupriDyne, a novel iodine complex, in inactivating SARS-CoV-2, showing 99% reduction in virus titers after 30 minutes.

The neonatal Fc receptor is a pan-echovirus receptor

This study identifies the neonatal Fc receptor (FcRn) as a receptor for all echoviruses, explaining increased neonatal susceptibility to these viruses.