Author

M. Agrawal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell-cell communication· 2 Organism:E. coli· 2

Frequent Co-Authors

D. Houbaert· 2 shared G. Bergers· 2 shared G. Shankar· 2 shared K. V. Venkatesh· 2 shared L. Boon· 2 shared M. Ganne· 2 shared M. S. Tirumkudulu· 2 shared N. D. Hysmith· 2 shared

Activity by Year

2021-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

D. Houbaert

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Mucosal and systemic immune dynamics associated with COVID-19 outcomes: a longitudinal prospective clinical study

M. Agrawal, A. S. Flores-Torres, J. S. Franks, S. Y. Lang, T. P. Fabrizio, K. E. McNair, L. V. Boywid, A. J. Blair, C. N. Hundman, N. D. Hysmith, M. A. Whitt, R. Keating, P. G. Thomas, R. J. Webby, A. M. Green, H. S. Smallwood

This study examines mucosal and systemic immune dynamics in a diverse cohort of children and adults with COVID-19, identifying immune markers associated with disease severity and outcomes.

bioRxiv · Aug 4, 2023 · PreprintImmunology

An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

D. Houbaert, A. P. Nikolakopoulos, O. Mece, K. Jacobs, J. Roels, G. Shankar, M. Agrawal, S. More, M. Ganne, K. Rillaerts, L. Boon, M. Swoboda, M. Nobis, L. Mourao, F. M. Bosisio, , P. Agostinis

This study shows that autophagy in lymphatic endothelial cells controls T cell egress from lymph nodes, which is critical for immune checkpoint therapy effectiveness.

bioRxiv · Jul 17, 2023Immunology

Establishing thresholds for cytokine storm and defining their relationship to disease severity in respiratory viral infections

A. Souquette, J. C. Crawford, J. Wolf, A. Blair, M. Agrawal, L. Boywid, K. McNair, N. D. Hysmith, C. Hundman, A. Bahadoran, S. R. Arnold, SJTRC Study Team, H. Smallwood, A. Green, P. G. Thomas

This study identifies cytokine thresholds and their relationship to disease severity in respiratory viral infections, showing that hypercytokinemia is not strongly linked to severity and that certain cytokines may predict long COVID risk.

bioRxiv · Jul 6, 2023 · PreprintImmunology

TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA

J. Verhoeven, K. A. Jacobs, F. Rizzollo, F. Lodi, Y. Hua, J. Pozniak, A. N. Srinvasan, D. Houbaert, G. Shankar, S. More, M. B. Schaaf, N. Dubroja Lakic, M. Ganne, J. Lamote, J. Van Weyenbergh, , P. Agostinis

This study shows that autophagy in tumor endothelial cells suppresses antitumor immunity in melanoma by promoting an immunosuppressive phenotype, and its inhibition enhances T cell infiltration and restricts tumor growth.

bioRxiv · Apr 21, 2023Cancer Biology

Anti-integrin αvβ6 autoantibodies are a novel predictive biomarker in ulcerative colitis

A. E. Livanos, A. Dunn, J. Fischer, R. C. Ungaro, W. Turpin, S.-H. Lee, S. Rui, D. M. Del Valle, J. J. Julia, G. Martinez-Delgado, M. S. Riddle, J. A. Murray, R. M. Laird, J. Torres, M. Agrawal, , S. Mehandru

This study identifies anti-integrin αvβ6 autoantibodies as a predictive biomarker for ulcerative colitis, showing they precede diagnosis by up to 10 years and correlate with adverse outcomes.

bioRxiv · Nov 21, 2022 · PreprintImmunology

Ligand Sensing Enhances Bacterial Flagellar Motor Output via Stator Recruitment

F. Naaz, M. Agrawal, S. Chakraborty, M. S. Tirumkudulu, K. V. Venkatesh

This study shows that bacteria can modulate flagellar motor speed through ligand sensing, not just altering rotation bias, with metabolisable ligands causing prolonged speed increases.

eLife · Apr 6, 2021Peer-reviewedBiophysics

Effect of ligand sensing on flagellar bundle formation in bacteria

M. Agrawal, S. Chakraborty, M. S. Tirumkudulu, K. V. Venkatesh

This study shows that ligand sensing in E. coli increases flagellar bundle tightness and swimming speed by enhancing motor torque and CCW bias, independent of metabolism.

bioRxiv · Feb 11, 2021 · PreprintBiophysics