M. DasGupta

Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography

The paper uses XFEL crystallography to observe conformational changes in an enzyme during catalysis, revealing ionization-linked dynamics that control catalytic activity.

Nodulin 16 of Lotus japonicus (Nlj16) regulates the recruitment of Leghemoglobin (LegH) to the infected nodule cell membrane during symbiotic nitrogen fixation

This study shows that Nlj16 recruits LegH to the membrane of infected nodule cells, essential for oxygen sequestration during symbiotic nitrogen fixation.

Redox-controlled structural reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography

The paper uses serial femtosecond crystallography to study redox-induced structural changes in the R2b-NrdI complex, revealing flavin strain and its role in superoxide generation.

Reproducibility of protein X-ray diffuse scattering and potential utility for modeling atomic displacement parameters

Turanose induced WOX5 restores symbiosis in the Medicago truncatula cytokinin perception mutant cre1

Turanose and WOX5 overexpression restore symbiosis in the cytokinin perception mutant cre1 by modulating auxin conjugate hydrolase MtIAR33.

Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis

This study uses mix-and-inject XFEL crystallography to observe conformational changes in isocyanide hydratase during catalysis, showing how cysteine modification affects enzyme dynamics and function.

Nuclear hormone receptor NHR-49 shapes immuno-metabolic response of Caenorhabditis elegans to Enterococcus faecalis infection.

This study shows that NHR-49 in C. elegans regulates lipid metabolism and immune responses to E. faecalis infection, linking lipid droplet homeostasis to survival.

A phylogenetic framework of the legume genus Aeschynomene for comparative genetic analysis of the Nod-dependent and Nod-independent symbioses

This paper constructs a phylogeny of Aeschynomene legumes to study Nod-dependent and Nod-independent symbioses, identifying suitable species for comparative genetic analysis.

Transcriptomic analysis with the progress of symbiosis in ‘crack-entry’ legume Arachis hypogaea highlights its contrast with ‘infection thread’ adapted legumes

This study compares the transcriptomic profiles of symbiosis progression in crack-entry legume Arachis hypogaea with infection thread-adapted legumes, identifying key gene expression differences.