Author

L. Che

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

X. Li· 2 shared A. Choi· 1 shared A. Pitea· 1 shared A. Zhou· 1 shared C. Qin· 1 shared D. Swaney· 1 shared E. McCarthy· 1 shared F. Du· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

X. Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The segmented flavivirus Alongshan virus reduces mitochondrial mass via degrading STAT2 to suppress innate immune response

Y. Zhao, L. Sui, M. Pan, F. Jin, Y. Huang, S. Fang, M. Wang, L. Che, W. Xu, N. Liu, N. Liu, H. Gao, Z. Hou, F. Du, Z. Wei, , Q. Liu

bioRxiv · Mar 6, 2024Microbiology

Tumors cells with mismatch repair deficiency induce hyperactivation of Pyroptosis resistant to cell membrane damage but are more sensitive to Co-treatment of IFN-γ and TNF-α to PANoptosis

H. Li, H. Ni, Y. Li, A. Zhou, X. Qin, Y. Li, L. Che, H. Mo, C. Qin, J. Li

The paper shows that dMMR tumor cells are resistant to membrane damage but sensitive to IFN-γ and TNF-α co-treatment inducing PANoptosis, suggesting a strategy to enhance ICB therapy.

bioRxiv · Jul 28, 2023Cancer Biology

HBV rewires liver cancer signaling by altering PP2A complexes

A. Pitea, R. Turnham, M. Eckhardt, G. M. Jang, Z. Xu, H. C. Lim, A. Choi, J. Von Dollen, R. S. Levin, J. T. Webber, E. McCarthy, J. Hu, X. Li, L. Che, G. Chan, , J. Gordan

This study identifies how HBV alters PP2A complexes to drive liver cancer signaling, revealing potential therapeutic targets.

bioRxiv · Mar 15, 2023 · PreprintCancer Biology

Millet-based supplement restored microbiota diversity of acute undernourished pigs

X. Li, Y. Hui, J. Ren, Y. Song, S. Liu, L. Che, X. Peng, X. Dai

The study shows that millet-based supplements improve gut microbiota diversity in undernourished pigs more effectively than corn-based supplements.

bioRxiv · Dec 13, 2019 · PreprintMicrobiology