M. Iqbal

Polymer-mediated oligonucleotide delivery enables construction of barcoded 3D cultures for spatial single-cell analysis

The paper introduces a method to create barcoded 3D cell cultures for spatial single-cell analysis using polymer-mediated oligonucleotide delivery and multiplex single-cell RNA sequencing.

Investigation of H9N2 avian influenza immune escape mutant that lacks haemagglutination activity

This paper identifies an H9N2 avian influenza virus mutant with a G149E mutation in HA that loses haemagglutination activity but retains replication fitness, highlighting challenges for vaccine and surveillance efforts.

Functional copy number variation in SQUALENE EPOXIDASE-LIKE genes affects photosystem II efficiency in Arabidopsis

This study identifies a quantitative trait locus for photosystem II efficiency in Arabidopsis caused by functional copy number variation in SQE-like genes.

Mapping the interaction sites of Influenza A viruses and human complement Factor H

This study maps the interaction sites between Influenza A viruses and human complement Factor H, showing strain-specific effects on viral entry and replication.

Risk Assessment of the newly emerged H7N9 avian influenza viruses

This study assesses the zoonotic risk of recent H7N9 avian influenza viruses by analyzing their receptor binding, stability, and immune escape properties compared to earlier strains.

Antigenic characterisation of human monoclonal antibodies for therapeutic use against H7N9 avian influenza virus

This study characterizes human monoclonal antibodies against H7N9 avian influenza virus, identifies key epitopes, and evaluates escape mutants' impact on viral fitness and immune evasion.

The origin of internal genes contributes to the replication and transmission fitness of H7N9 avian influenza virus

This study shows that internal gene segments from different H9N2 lineages affect the replication and transmission fitness of H7N9 avian influenza viruses in chickens and their zoonotic potential.

Co-infection of chickens with H9N2 and H7N9 avian influenza viruses leads to emergence of reassortant H9N9 virus with increased fitness for poultry and enhanced zoonotic potential

Genetic determinants of receptor-binding preference and zoonotic potential of H9N2 avian influenza viruses

This study identifies genetic mutations in H9N2 influenza viruses that influence their receptor-binding preferences and zoonotic potential by altering their affinity for human-like or avian receptors.

Immunogenicity and Protective Efficacy of an Intranasal Live-attenuated Vaccine Against SARS-CoV-2 in Preclinical Animal Models

This study evaluates an intranasal live-attenuated vaccine against SARS-CoV-2 in mice and hamsters, showing high immunogenicity and complete protection from disease and viral shedding.

An assessment of efficacy of Iodine complex (Renessans) against SARS-CoV-2 in non-human primates (Rhesus macaque)

This study evaluates the efficacy of Renessans, an iodine complex, against SARS-CoV-2 in Rhesus macaques, showing reduced viral load and faster clearance in treated groups.

Adipocyte REVERBα dictates adipose tissue expansion during obesity

This study shows adipocyte REVERBα regulates metabolic processes in white adipose tissue during obesity, preventing inflammation and fibrosis without affecting daily lipogenesis rhythms.

Contribution of segment 3 to the acquisition of virulence in contemporary H9N2 avian influenza viruses

This paper identifies a single amino acid change in the PA protein of H9N2 avian influenza viruses that enhances virulence and replication in poultry.

PA-X is an avian virulence factor in H9N2 avian influenza virus

This study investigates the role of PA-X in H9N2 avian influenza viruses, finding it enhances replication in mammalian cells and contributes to virulence in chickens.

Competitive approach of invasive cocklebur (Xanthium strumarium) with native weed species diversity in Northeast China

This study examines how invasive Xanthium strumarium affects native weed diversity in Northeast China through field experiments and statistical analysis.

Phytochemical screening, GC-MS profiling of invasive cocklebur (Xanthium strumarium)-insect-pathogen interaction and simulated volatile chemical signaling at Northeast China

The paper investigates how latitude affects insect and fungal infestation of Xanthium strumarium and uses GC-MS to analyze chemical defenses in response to pathogens.

Article The Genotype Diversity within the H5N8 Influenza A Subtype

The paper analyzes genotype diversity in H5N8 influenza A subtype using sequence data to identify reassortment events in Guangdong and non-Guangdong variants.

The molecular basis of antigenic variation among A(H9N2) avian influenza viruses

This study identifies molecular mechanisms of immune escape in H9N2 avian influenza viruses through genetic analysis and experimental validation, highlighting the role of glycosylation and receptor-binding avidity.