S. Jansen

Time-based shifts in xylem vulnerability curves of angiosperms based on the flow-centrifuge method

This study shows that spin time affects xylem vulnerability curves in angiosperms, leading to shifts in hydraulic conductivity and P50 values when using the flow-centrifuge method.

Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility

This study shows that the ACTA1 R256H mutation disrupts actin structure and function in cardiomyocytes, leading to reduced contractility and a likely causative role in dilated cardiomyopathy.

Thermal acclimation of stem respiration reduces global carbon burden

The paper predicts and validates the temperature sensitivity of stem respiration, showing thermal acclimation reduces global carbon emissions.

Functional copy number variation in SQUALENE EPOXIDASE-LIKE genes affects photosystem II efficiency in Arabidopsis

This study identifies a quantitative trait locus for photosystem II efficiency in Arabidopsis caused by functional copy number variation in SQE-like genes.

PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency

This study identifies PCID2 as a novel HIV-1 latency-promoting factor that represses transcription and dysregulates viral RNA processing through its role in the TREX2 complex.

SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

This study identifies SOD1 as a synthetic lethal target in PPM1D-mutant leukemia cells through CRISPR/Cas9 screening, revealing a dysregulated redox landscape and potential therapeutic strategy.

Xylem sap residue in cut-open conduits can affect gas discharge in pneumatic experiments

The paper investigates how residual xylem sap in cut conduits affects gas discharge measurements in pneumatic experiments and proposes a correction method.

IST1 regulates select endosomal recycling pathways

This study shows IST1 is involved in specific endosomal recycling pathways by interacting with SNX15 and CHMP1B to regulate cargo transport from early/sorting endosomes.

Gas diffusion kinetics drive embolism spread in angiosperm xylem: evidence from flow-centrifuge experiments and modelling

The paper measures hydraulic conductivity changes in angiosperm xylem over time under different temperatures and pressures, showing gas diffusion kinetics influence embolism spread.

Lianas in tropical dry forests have higher embolism resistance but similar hydraulic efficiency than lianas in rainforests

This study compares hydraulic traits of lianas in seasonal dry forests and rainforests, finding higher embolism resistance but similar efficiency in seasonal forest lianas.

Biodistribution and Environmental Safety of a Live-attenuated YF17D-vectored SARS-CoV-2 Vaccine Candidate

This study evaluates the safety and biodistribution of a YF17D-vectored SARS-CoV-2 vaccine candidate in hamsters, showing improved safety compared to parental YF17D.

Dynamic changes in gas solubility of xylem sap reiterate the enigma of plant water transport under negative pressure

The paper measures gas solubility in xylem sap under varying conditions and finds non-equilibrium patterns that suggest plants can transport water under negative pressure with dissolved gas buffering.

Polar lipids are linked to nanoparticles in xylem sap of temperate angiosperm species

The paper examines the relationship between nanoparticle and lipid concentrations in xylem sap of six temperate angiosperm species and finds significant correlations in three species.

A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1

The paper identifies LCS3, a compound that induces oxidative stress in lung cancer cells by inhibiting disulfide reductases GSR and TXNRD1, and shows its synergistic effect with glutathione and thioredoxin pathway inhibition.

Accuracy of the pneumatic method for estimating xylem vulnerability to embolism in temperate diffuse-porous tree species

The paper compares pneumatic and flow-centrifuge methods for estimating xylem embolism resistance in temperate tree species, finding high agreement in some parameters but variability in others.

A Unit Pipe Pneumatic model to simulate gas kinetics during measurements of embolism in excised angiosperm xylem

The paper develops a Unit Pipe Pneumatic model to simulate gas diffusion kinetics in xylem embolism measurements and finds it overestimates embolism resistance by 2-17%.

A user manual to measure gas diffusion kinetics in plants: Pneumatron construction, operation and data analysis

This paper provides a manual for constructing, operating, and analyzing data from the Pneumatron device, which measures gas diffusion kinetics in plant xylem.

Quaternary climate change explains global patterns of tree beta-diversity

The paper examines how Quaternary climate change influences tree beta-diversity globally, finding temperature changes since the Last Glacial Maximum strongly affect turnover and nestedness components.

Minding The Gap: Range Size And Economic Use Drive Functional Trait Data Shortfall In The Atlantic Forest

The paper identifies factors driving functional trait data gaps in the Atlantic Forest, finding larger gaps for small-ranged and economically used species, and in eastern regions away from urban areas.

Pore constrictions in intervessel pit membranes reduce the risk of embolism spreading in angiosperm xylem

The paper investigates how pore constrictions in pit membranes relate to embolism resistance in angiosperm xylem and finds that pit membrane thickness strongly influences constriction size and embolism resistance.

Lipids in xylem sap of woody plants across the angiosperm phylogeny

The paper analyzes lipid composition in xylem sap of seven angiosperm species, finding galactolipids and phospholipids, and suggests apoplastic lipids affect water transport theory.

Identification of TMEM106B as proviral host factor for SARS-CoV-2

This study identifies TMEM106B as a host factor essential for SARS-CoV-2 infection and replication in human cells.

A semi-automated method for measuring xylem vessel length distribution

This paper introduces a semi-automated method to measure xylem vessel length distribution using a Pneumatron device and software, enabling faster and more efficient analysis.

N-terminal modification of actin by acetylation and arginylation determines the architecture and assembly rate of linear and branched actin networks

This study shows that acetylation and arginylation of actin's N-terminus differentially regulate actin polymerization dynamics and remodeling by actin-binding proteins, affecting network architecture and assembly rates.

Paleoclimate and current climate collectively shape the phylogenetic and functional diversity of trees worldwide

The paper maps global tree diversity patterns and shows that both current and ancient climates influence tree species richness, functional, and phylogenetic diversity.

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

This study shows that STAT2 signaling both restricts SARS-CoV-2 spread and causes severe pneumonia in infected hamsters.

Half of the world's tree biodiversity is unprotected and is increasingly threatened by human activities

The paper identifies priority areas for global tree conservation and finds that half are unprotected and face human threats.

Root xylem in three woody angiosperm species is not more vulnerable to embolism than stem xylem

The paper compares embolism resistance between root and stem xylem in three woody angiosperms, finding roots are more resistant in some species but not all.

Does the leaf economic spectrum hold within plant functional types? A Bayesian multivariate trait meta-analysis

The paper examines if leaf economic relationships exist within plant functional types using a Bayesian multivariate model and finds they are generally consistent but vary in strength across types.