M. Ishikawa

Universal pretreatment development for low-input proteomics using Lauryl Maltose Neopentyl Glycol

The paper develops a low-input proteomics method called LASP to improve peptide recovery and reduce MS contamination, achieving 1,175 proteins identified per single cell.

Mapping adipocyte interactome networks by HaloTag enrichment mass-spectrometry

The paper introduces HaloMS, a high-throughput method for mapping protein interactions in adipocytes, identifying new transcription factor complexes and networks.

A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human Primates

A tetravalent dengue VLP vaccine induces neutralizing antibodies and reduces viral replication in non-human primates without ADE.

Bioorthogonal chemical labelling of endogenous neurotransmitter receptors in living mouse brains

This paper develops a method to label endogenous neurotransmitter receptors in living mouse brains using LDAI chemistry, enabling spatial mapping and dynamic analysis of receptors in health and disease.

Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae

This study presents cryo-EM structures of Na+-NQR from Vibrio cholerae with and without inhibitors, revealing cofactor arrangements and inhibitor binding sites.

Affective arousal explains infant gaze following under various social context

This study shows that infant gaze following is influenced by social context through physiological arousal, mediated by heart rate changes in response to reliable faces and eye contact.

Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice

This study investigates how Porphyromonas gingivalis LPS affects cardiac function in mice via TLR4 signaling, showing that TLR4 inhibition improves cardiac function.

Endothelial metastasis-associated protein 1 (MTA1) is an essential molecule for angiogenesis

This study shows that MTA1 is essential for angiogenesis by promoting tube formation in endothelial cells and that its pathway differs from the VEGF-VEGF receptor 2 pathway.

Single-cell transcriptome analysis of Physcomitrella leaf cells during reprogramming using microcapillary manipulation

The paper introduces 1cell-DGE, a single-cell RNA-sequencing method using microcapillary manipulation to analyze gene expression in intact moss tissues, identifying differentially expressed genes during leaf cell reprogramming.