P. Pan

Engineered 3D environments reprogram fibroblast-mediated inflammation in rheumatoid Arthritis.

This study shows that 3D environments influence fibroblast inflammation in rheumatoid arthritis, with soft hydrogels promoting a resolving phenotype and stiff scaffolds restoring inflammatory profiles.

CD20+ T cells are associated with inflammatory responses in experimental arthritis.

This study identifies CD20+ T cells as inflammatory contributors in murine arthritis, showing their expansion and cytokine production in lymph nodes and joints.

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

This study identifies that DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junctions, suggesting MMP-9 as a potential therapeutic target for severe dengue.

Identification of differentially expressed genes in the longissimus dorsi muscle of Luchuan and Duroc pigs by transcriptome sequencing

The paper identifies differentially expressed genes in the longissimus dorsi muscle of Luchuan and Duroc pigs, highlighting genes related to muscle development and metabolic pathways.

Paxillin Promotes ATP-induced Activation of P2X7 Receptor and NLRP3 Inflammasome

This study identifies Paxillin's role in promoting ATP-induced activation of P2X7 receptor and NLRP3 inflammasome through complex formation and deubiquitination.

STING recruits NLRP3 to the ER and deubiquitinates NLRP3 to activate the inflammasome

This study shows STING activates the NLRP3 inflammasome by recruiting NLRP3 to the ER and deubiquitinating it, enhancing IL-1β secretion and inflammatory responses.