Author

N. Saini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Sarin· 2 shared A. Agarwal· 1 shared A. Dutta· 1 shared A. Naaz· 1 shared A. Ramanathan· 1 shared A. Tiwari· 1 shared A. Vivekanand· 1 shared A. Walvekar· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

A. Sarin

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PROTEOMICS OF HYPOTHERMIC ADAPTATION REVEALS THAT RBM3 ENHANCES MITOCHONDRIAL METABOLISM AND MUSCLE STEM-CELL DIFFERENTIATION

A. Ramanathan, P. Dey, S. Rajalaxmi, P. S. Thakur, M. A. Hashmi, H. Lal, N. Saini, S. Muralidharan, R. G. H. Math, P. Saha, S. S. Pundlik, N. Singh

This study identifies RBM3 as a key mediator of hypothermic adaptation in skeletal muscle myoblasts, showing it enhances mitochondrial metabolism and muscle stem-cell differentiation.

bioRxiv · May 5, 2023 · PreprintBiochemistry

Methionine uptake via SLC43A2 transporter is essential for regulatory T lymphocyte survival

A. Naaz, N. Saini, S. Padma, P. Gahlot, A. Walvekar, A. Dutta, U. Davathamizhan, A. Sarin, S. Laxman

The paper identifies methionine uptake via SLC43A2 as essential for Treg survival during IL-2 deprivation, regulated by Notch1.

bioRxiv · Mar 9, 2022 · PreprintImmunology

Effects of substrate stiffness and actin velocity on fibronectin fibril morphometry and mechanics

S. H. Weinberg, N. Saini, C. Lemmon

This study uses a computational model to investigate how cell contractility and tissue stiffness influence fibronectin fibril formation and mechanics.

bioRxiv · Feb 24, 2021Biophysics

Integrated genomic view of SARS-CoV-2 in India

P. Kumar, R. Pandey, P. Sharma, M. Dhar, A. Vivekanand, U. Bharathram, H. Vashistha, S. Wadhwa, N. Tyagi, S. Fatihi, U. Sharma, P. Singh, H. Lall, M. Datta, P. Gupta, , P. Rakshit

The paper analyzes SARS-CoV-2 genomic data from India to trace introduction and local transmission, identifying multiple clades and highlighting the need for molecular surveillance.

Wellcome Open Research · Aug 3, 2020Peer-reviewedMicrobiology

Signaling activated by nucleolar localised Notch4 Intracellular Domain underlies protection from genomic damage

N. Saini, A. Sarin

This study identifies a Notch4 signaling cascade activated by nucleolar localization of NIC4 that protects cells from genotoxic damage and regulates ribosome biogenesis.

bioRxiv · Jun 13, 2019 · PreprintCancer Biology

MiR-195 regulates mitochondrial function by targeting mitofusin-2 in breast cancer cells

P. K. Purohit, R. Edwards, K. Tokatlidis, N. Saini

This study shows miR-195 regulates mitochondrial function by targeting mitofusin-2, leading to mitochondrial fission and altered oxidative stress in breast cancer cells.

bioRxiv · Nov 22, 2018Cancer Biology