Author

O. Khatun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Organism:mouse· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

S. Tripathi· 6 shared R. Narayan· 4 shared A. Biji· 2 shared M. Sharma· 2 shared P. Rani· 2 shared S. Das· 2 shared A. A. Dey· 1 shared A. Singh· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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6 shared papersMicrobiology

S. Tripathi

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

S. Mishra, D. Jain, A. A. Dey, S. Nagaraja, M. Srivastava, O. Khatun, K. Balamurugan, M. Anand, S. Tripathi, M. Ganji, S. Kesavardhana

The paper identifies viral RHIMs in bat RNA viruses that regulate host cell death through Z-RNA sensing and ZBP1-RIPK3 signaling, revealing species-specific effects on human and bat cells.

bioRxiv · Aug 23, 2023Immunology

SARS-CoV-2 variants exhibit differential gut tropism and dysbiosis in Syrian golden hamsters.

S. K. Nagraj, C. M. Joy, R. Narayan, R. Shiraz, S. Kaur, O. Khatun, S. Dubey, J. Ng, N. MISHRA, S. Tripathi

This study examines SARS-CoV-2 variants' gut tropism and impact on gut microbiota in Syrian golden hamsters, finding Delta's stronger gastrointestinal preference and greater microbial dysbiosis.

bioRxiv · Jun 19, 2023 · PreprintPathology

HuR enhances SARS-CoV-2 non-structural protein translation through the genomic 5'-UTR, by promoting polypyrimidine tract-binding protein binding

H. Raheja, R. Sahu, T. Ghosh, P. Rani, B. George, O. Khatun, S. Tripathi, S. Das

This paper identifies HuR's role in enhancing SARS-CoV-2 non-structural protein translation via the 5'-UTR by promoting PTB binding, while suppressing structural protein translation, and shows potential therapeutic targeting of HuR.

bioRxiv · Mar 15, 2023Microbiology

ORF6 protein of SARS-CoV-2 inhibits TRIM25 mediated RIG-I ubiquitination to mitigate type I IFN induction.

O. Khatun, M. Sharma, R. Narayan, S. Tripathi

This study identifies ORF6 as a SARS-CoV-2 protein that inhibits TRIM25-mediated RIG-I ubiquitination, thereby blocking type I IFN induction and signaling.

bioRxiv · May 5, 2022 · PreprintMicrobiology

A natural broad-spectrum inhibitor of enveloped virus entry, effective against SARS-CoV-2 and Influenza A Virus in preclinical animal models.

R. Narayan, M. Sharma, R. T. Yadav, A. Biji, O. Khatun, R. S. Rajmani, P. R. Sharma, S. Jeyashankar, P. Rani, C. D. Rao, V. Satchidanandam, S. Das, R. Agarwal, S. Tripathi

This paper identifies picolinic acid as a broad-spectrum antiviral that inhibits enveloped virus entry, showing efficacy against SARS-CoV-2 and Influenza A Virus in animal models.

bioRxiv · Feb 16, 2022 · PreprintMicrobiology

Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples

A. Biji, O. Khatun, S. Swaraj, R. Narayan, R. Rajmani, R. Sardar, D. Satish, S. Mehta, H. Bindhu, M. Jeevan, D. K. Saini, A. Singh, D. Gupta, S. Tripathi

This study identifies prognostic markers and therapeutic targets for COVID-19 by analyzing Omics data from nasal and BALF samples, finding S100 family genes and TXN as key factors, and validating Auranofin as a potential treatment.

bioRxiv · Feb 18, 2021Microbiology