Author

P. Dagur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Larochelle· 2 shared C. Salisbury-Ruf· 2 shared D. Araki· 2 shared N. Redekar· 2 shared A. Abedini· 1 shared A. Krouse· 1 shared A. Z. Rosenberg· 1 shared B. Fisk· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

A. Larochelle

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning

D. Araki, S. Hong, N. Linde, B. Fisk, N. Redekar, C. Salisbury-Ruf, A. Krouse, T. Engels, J. Golomb, P. Dagur, D. M. Magnani, Z. Wang, A. Larochelle

This study explores using cMPL as a target to selectively deplete human hematopoietic stem cells, showing potential for safer pre-transplant conditioning.

bioRxiv · Feb 24, 2024 · PreprintCell Biology

Post-Transplant Administration of G-CSF Impedes Engraftment of Gene Edited Human Hematopoietic Stem Cells by Exacerbating the p53-Mediated DNA Damage Response

D. Araki, V. Chen, N. Redekar, C. Salisbury-Ruf, Y. Luo, P. Liu, Y. Li, R. Smith, P. Dagur, C. Combs, A. Larochelle

This study shows that post-transplant G-CSF administration impairs engraftment of CRISPR-edited HSPCs by worsening the p53 DNA damage response, but not unedited or lentiviral-transduced HSPCs.

bioRxiv · Jun 29, 2023Cell Biology

HIV viral protein R induces loss of DCT1-type renal tubules

K. Z. Latt, T. Yoshida, S. Shrivastav, A. Abedini, J. M. Reece, Z. Sun, H. Lee, K. Okamoto, P. Dagur, J. Heymann, Y. Zhao, J.-Y. Chung, S. Hewitt, P. A. Jose, K. Lee, , J. B. Kopp

This study shows HIV Vpr reduces DCT1-type renal tubules in mice, leading to salt wasting via apoptosis dysregulation of Slc12a3+ Pvalb+ cells.

bioRxiv · Feb 2, 2023 · PreprintPathology