Author

R. Sabarinathan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:variant calling· 2 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2

Frequent Co-Authors

A. Boot· 1 shared A. Budharaja· 1 shared A. CE· 1 shared A. D. Mavetkar· 1 shared A. K. Mukherjee· 1 shared A. K. Singh· 1 shared A. Perwez· 1 shared A. Sengupta· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Boot

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Author profile →

4 papers

Recent·Most cited

Androgen Receptor driven gene score identifies tumors with Epithelial to Mesenchymal Transition features in triple negative breast cancer

S. Rajarajan, S. VP, A. CE, M. Nair, A. D. Mavetkar, C. M. Naidu, S. Patil, V. P. Nimbalkar, M. Pillai, M. K. Jolly, R. Sabarinathan, R. S. Ramesh, S. BS, J. S. Prabhu

The paper develops an AR-driven gene score to identify tumors with EMT features in triple-negative breast cancer, finding AR high tumors have better clinical outcomes and higher EMT marker expression.

bioRxiv · Feb 21, 2023 · PreprintCancer Biology

Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

A. K. Mukherjee, S. Dutta, A. Singh, S. Sharma, S. S. Roy, A. Sengupta, M. Chatterjee, S. Vinayagamurthy, S. Bagri, D. Khanna, M. Verma, D. Soni, A. Budharaja, S. K. Bhisade, V. anand, , S. Chowdhury

The paper shows that telomere length modulates IL1R1 expression via TRF2 binding, affecting immune signaling and macrophage infiltration in TNBC.

bioRxiv · Dec 7, 2021 · PreprintCancer Biology

Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer

P. Bala, A. K. Singh, P. Kavadipula, V. Kotapalli, R. Sabarinathan, M. D. Bashyam

Oncogene · Dec 1, 2020Peer-reviewedCancer Biology

The Repertoire of Mutational Signatures in Human Cancer

L. Alexandrov, J. Kim, N. J. Haradhvala, M. N. Huang, A. W. T. Ng, Y. Wu, A. Boot, K. R. Covington, D. A. Gordenin, E. Bergstrom, S. M. A. Islam, N. Lopez-Bigas, L. J. Klimczak, J. R. McPherson, S. Morganella, , M. R. Stratton

The paper characterizes 49 mutational signatures in human cancer using a large dataset of somatic mutations, revealing associations with exposures and DNA repair mechanisms and identifying signatures of unknown origin.

bioRxiv · Jul 3, 2019Cancer Biology