Author

R. Sugimura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Zhang· 3 shared A. To· 2 shared P. Liu· 2 shared Y. Chao· 2 shared Y. Huang· 2 shared Y. Xiang· 2 shared A. Li· 1 shared A. Niwa· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersImmunology

S. Zhang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lipidic and senescent macrophages predict progression and response to combinatorial immunotherapy in triple-negative breast cancer

C. L. Chan, A. To, S. Zhang, J. W. H. Wong, Y. Huang, Y. Chao, R. Sugimura

bioRxiv · Jun 24, 2024 · PreprintCancer Biology

SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids

C. W. Chau, A. To, R. K. H. Au-Yeung, K. Tang, Y. Xiang, D. Ruan, L. Zhang, H. Wong, S. Zhang, M. T. Au, S. Chung, E. Song, D.-H. Choi, P. Liu, S. Yuan, , R. Sugimura

This study shows SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids, upregulating interferon signaling linked to cytokine release syndrome.

Scientific Reports · Apr 16, 2024Peer-reviewedImmunology

PD-L1 regulates inflammatory macrophage development from human pluripotent stem cells by maintaining interferon-gamma signal

H. Cao, Y. Xiang, S. Zhang, Y. Chao, J. Guo, J. W. K. Ho, Y. Huang, P. Liu, R. Sugimura

This study shows PD-L1 maintains IFN-gamma signaling in human pluripotent stem cell-derived macrophages, essential for their development and inflammatory function.

bioRxiv · Dec 14, 2022 · PreprintImmunology

Biomimetic Aorta-Gonad-Mesonephros on-a-Chip to Study Human Developmental Hematopoiesis

R. Sugimura, R. Ohta, C. Mori, A. Li, T. Mano, E. Sano, K. Kosugi, T. Nakahata, A. Niwa, M. K. Saito, Y.-s. Torisawa

The paper develops a microfluidic AGM-on-a-chip to study human developmental hematopoiesis and demonstrates its ability to induce endothelial-to-hematopoietic transition.

bioRxiv · Dec 23, 2019Bioengineering