Author

S. Basnet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Adhikari· 1 shared B. Aryal· 1 shared b. m. monks· 1 shared B. R. Bhattarai· 1 shared C. Du· 1 shared C. L. Magee· 1 shared D. Hu· 1 shared D. K. Poudel· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

B. Adhikari

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Author profile →

3 papers

Recent·Most cited

Proteasome inhibition induces DNA methylation alteration by attenuating the synthesis of DNA methyltransferase 1 and 3B in colorectal cancer

W. Zhou, Y. Sheng, D. Hu, Y. An, M. Yang, W. Wang, S. Basnet, J. Yan, S. Zhang, Q. Liu, Y. Li, Y. Tan, J. Gao, K. Sun, C. Du

This study shows proteasome inhibition alters DNA methylation in colorectal cancer by reducing DNMT1 and DNMT3B synthesis via AKT/mTOR inactivation.

bioRxiv · Jun 14, 2024Cancer Biology

In Silico Analysis of Secondary Metabolites that Modulates Enzymes of Cholesterol Target

R. Marahatha, S. Basnet, B. R. Bhattarai, P. Budhathoki, B. Aryal, B. Adhikari, G. Lamichhane, D. K. Poudel, N. Parajuli

This paper identifies sixteen secondary metabolites with inhibitory activity against XO and HMGR through in-silico analysis, showing potential as drug candidates for hypercholesterolemia treatment.

bioRxiv · Jul 24, 2020 · PreprintBiochemistry

Pre-existing Technological Core and Roots for the CRISPR Breakthrough

C. L. Magee, P. W. Kleyn, b. m. monks, U. Betz, S. Basnet

This paper analyzes the technological origins of CRISPR by examining patent citations and identifies key prior technologies contributing to its development.

bioRxiv · May 24, 2018Bioengineering