Author

S. Bohlander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. Zhou· 1 shared C. Walsh· 1 shared C. Wang· 1 shared D. Zhou· 1 shared G. Xu· 1 shared H. Gao· 1 shared J. Huang· 1 shared J. Xie· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. Zhou

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1 paper

Recent·Most cited

STING-dependent cytosolic DNA sensing pathway drives the progression to leukemia in TET2-mutated HSPCs

J. Xie, M. Sheng, S. Rong, C. Wang, W. Wu, J. Huang, Y. Sun, P. Chen, Y. Wu, Y. Wang, L. Wang, B. Zhou, X. Huang, C. Walsh, S. Bohlander, , G. Xu

This study shows that TET2 mutations cause DNA damage, activating the cGAS-STING pathway, which drives clonal hematopoiesis and leukemia, and that STING inhibition can suppress these effects in mouse and patient models.

bioRxiv · Dec 17, 2022 · PreprintCancer Biology