Author

S. Rong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Blomberg· 1 shared A. Damian-Serrano· 1 shared A. P. Fischer· 1 shared A. Tkachev· 1 shared B. M. Henn· 1 shared B. Shen· 1 shared B. Treutlein· 1 shared B. Zhou· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

A. Blomberg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

STING-dependent cytosolic DNA sensing pathway drives the progression to leukemia in TET2-mutated HSPCs

J. Xie, M. Sheng, S. Rong, C. Wang, W. Wu, J. Huang, Y. Sun, P. Chen, Y. Wu, Y. Wang, L. Wang, B. Zhou, X. Huang, C. Walsh, S. Bohlander, , G. Xu

This study shows that TET2 mutations cause DNA damage, activating the cGAS-STING pathway, which drives clonal hematopoiesis and leukemia, and that STING inhibition can suppress these effects in mouse and patient models.

bioRxiv · Dec 17, 2022 · PreprintCancer Biology

Sequencing uracil in DNA at single-nucleotide resolution

L. Jiang, J. Yin, M. Qian, S. Rong, K. Chen, C. Zhao, Y. Tan, J. Guo, H. Chen, S. Gao, T. Liu, Y. Liu, B. Shen, J. Yang, Y. Zhang, , Y.-H. Chen

This paper introduces SNU-seq, a method for single-nucleotide uracil mapping in DNA, validated on synthetic DNA and mammalian genomes, revealing uracil dynamics in treated cells and AID hotspots.

bioRxiv · Jun 14, 2021 · PreprintBiochemistry

Ecological load and balancing selection in circumboreal barnacles

J. C. B. Nunez, S. Rong, A. Damian-Serrano, J. T. Burley, R. Elyanow, D. A. Ferranti, K. B. Neil, H. Glenner, M. A. Rosenblad, A. Blomberg, K. Johannesson, D. M. Rand

The paper identifies balancing selection in circumboreal barnacles, showing 4% of genes are maintained across 2 million years, with functions in ion regulation, pain reception, and heat tolerance.

bioRxiv · Jul 18, 2020Evolutionary Biology

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains

E. Khrameeva, I. Kurochkin, D. Han, P. Guijarro, S. Kanton, M. Santel, Z. Qian, S. Rong, P. Mazin, M. Bulat, O. Efimova, A. Tkachev, S. Guo, C. Sherwood, G. Camp, , P. Khaitovich

The paper identifies gene expression differences between human and non-human primate brains at single-cell resolution, revealing rapid evolution in specific cell types.

bioRxiv · Sep 10, 2019Evolutionary Biology

Localization of adaptive variants in human genomes using averaged one-dependence estimation

L. A. Sugden, E. G. Atkinson, A. P. Fischer, S. Rong, B. M. Henn, S. Ramachandran

The paper introduces SWIF(r), a probabilistic method to detect selective sweeps and localize adaptive mutations in human genomes using population-genetic data.

bioRxiv · Dec 4, 2017Evolutionary Biology