S. Jindal

Myeloid-specific KDM6B inhibition sensitizes Glioblastoma to PD1 blockade

This study shows that inhibiting KDM6B in myeloid cells improves response to PD1 blockade in glioblastoma by enhancing anti-tumor immunity.

Stepwise origin and evolution of a transcriptional activator and repressor system integrating nutrient signaling in plants

This study identifies the stepwise origin and evolution of a transcriptional activator-repressor system in plants through evolutionary analysis and phylogenetic reconstruction.

Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer.

Preventing weight gain after ovariectomy reduces tumor burden and obesity-related factors in rodent models of postmenopausal breast cancer.

Mutant strains of Escherichia coli lacking global regulators, arcA and fis, demonstrate better growth fitness by pathway reprogramming under acetate metabolism

This study shows that E. coli mutants lacking arcA and fis grow faster under acetate metabolism due to metabolic reprogramming, with increased TCA cycle flux and reduced gluconeogenesis.

A negative feedback loop of the TOR signaling moderates growth and enables rapid sensing of stress signals in plants

This study identifies a negative feedback loop involving FLZ8 and SnRK11 that modulates TOR signaling in Arabidopsis, enabling growth regulation and stress response.

A palette of fluorophores that are differentially accumulated by wild-type and mutant strains of Escherichia coli: surrogate ligands for bacterial membrane transporters

The paper identifies 39 fluorophores differentially accumulated by wild-type and mutant E. coli strains, serving as surrogates for bacterial membrane transporter assays.

S-nitrosylated and non-nitrosylated COX2 has differential expression and distinct subcellular localization in normal and breast cancer tissue

The paper examines differential expression and subcellular localization of S-nitrosylated and non-nitrosylated COX2 in normal and breast cancer tissue using multiple antibody clones.

Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli

This study uses flow cytometry to assess dye uptake in E. coli knockout strains, revealing multiple transporters involved in dye accumulation and questioning their use as bioenergetic or DNA quantification tools.

Very rapid flow cytometric assessment of antimicrobial susceptibility during the apparent lag phase of microbial (re)growth

This study uses flow cytometry to rapidly assess antimicrobial susceptibility during the lag phase of E. coli growth, showing susceptibility can be detected within 20 minutes.