M. Anwar

Human left ventricle circRNA-miRNA-mRNA network analyses reveals a novel proangiogenic role for circNPHP1 under ischemic conditions

This study identifies a circRNA-miRNA-mRNA network in ischemic heart disease, revealing circNPHP1's role in enhancing angiogenesis by sponging miR-221-3p to upregulate VEGF-A and BCL2.

Endothelial ERG programs neutrophil transcriptome for sustained anti-inflammatory vascular niche

This study shows that endothelial ERG regulates neutrophil transcriptome to create an anti-inflammatory vascular niche, preventing excessive inflammation.

An Engineered IGF2 Mutant for Lysosomal Targeting Chimeras Development and Membrane Proteins Degradation

This paper introduces eiLYTACs, an engineered IGF2-based technology that degrades membrane proteins and inhibits tumor growth by avoiding IGF1R activation.

Towards A Wireless Image Sensor for Real-Time Fluorescence Microscopy in Cancer Therapy

The paper presents a wireless, lensless CMOS image sensor for real-time fluorescence microscopy in cancer therapy, demonstrating its ability to image immune cells in lymph nodes.

Multicolor fluorescence microscopy for surgical guidance using a chip-scale imager with a low-NA fiber optic plate and a multi-bandpass interference filter

This paper introduces a compact, lens-less fluorescence imaging chip for surgical guidance, capable of multiplexed detection and high-resolution imaging of tumor and nerve structures.

Tension sensing by FAK governs nuclear mechanotransduction, endothelial transcriptome and fate

This study shows that FAK-mediated tension sensing in endothelial cells regulates nuclear mechanotransduction, transcriptome, and cell fate, crucial for maintaining a restrictive endothelial barrier.

An assessment of efficacy of Iodine complex (Renessans) against SARS-CoV-2 in non-human primates (Rhesus macaque)

This study evaluates the efficacy of Renessans, an iodine complex, against SARS-CoV-2 in Rhesus macaques, showing reduced viral load and faster clearance in treated groups.

Signal to Noise Ratio as a Cross-Platform Metric for Intraoperative Fluorescence Imaging

The paper introduces and evaluates the signal-to-noise ratio (SNR) as a metric for intraoperative fluorescence imaging to improve the detection of microscopic tumor foci during cancer surgery.