Author

S. Renner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Wolf· 2 shared A. Ali· 1 shared A. Boettcher· 1 shared A. Deik· 1 shared A. Farsidjani· 1 shared A. Ivanova· 1 shared A. Kostina· 1 shared A. Muir· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

E. Wolf

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

K. L. Abbott, A. Ali, D. Casalena, B. T. Do, R. Ferreira, J. H. Cheah, C. K. Soule, A. Deik, T. Kunchok, D. R. Schmidt, S. Renner, S. E. Honeder, M. Wu, S. H. Chan, T. Tseyang, , M. G. Vander Heiden

The paper screens compounds targeting metabolism in serum-derived medium to identify differential responses in cancer cells, aiming to improve drug response prediction.

bioRxiv · Feb 25, 2023Cancer Biology

Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome

E. Neuwirt, G. Magnani, T. Cikovic, A. Kostina, S. Wohrle, S. Flemming, N. J. Fischenich, B. S. Saller, O. Gorka, S. Renner, C. Agarinis, C. Parker, A. Boettcher, C. J. Farady, R. Backofen, , O. Gross

A small molecule screen identifies tyrosine kinase inhibitors that cause lysosomal damage, leading to cell lysis and NLRP3 inflammasome activation via K+ efflux.

bioRxiv · Feb 19, 2022 · PreprintImmunology

Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs

E. Kemter, A. Müller, M. Neukam, A. Ivanova, N. Klymiuk, S. Renner, K. Yang, J. Broichhagen, M. Kurome, V. Zakhartchenko, B. Kessler, K.-P. Knoch, M. Bickle, B. Ludwig, K. Johnsson, , M. Solimena

This study develops a transgenic pig model with SNAP-tagged insulin to investigate in vivo insulin secretory granule dynamics and turnover.

bioRxiv · Apr 23, 2021Cell Biology

Chronic hyperglycaemia drives functional impairment of lymphocytes in diabetic INSC94Y transgenic pigs

I.-M. Giese, S. Renner, E. Wolf, S. M. Hauck, C. A. Deeg

This study examines immune cell dysfunction in diabetic pigs, finding reduced T cell proliferation and altered metabolic activity linked to chronic hyperglycaemia.

bioRxiv · Aug 26, 2020Immunology