S. Sankaran

Thermo-amplifier circuit in probiotic E. coli for stringently temperature-controlled release of a novel antibiotic

The paper develops a thermo-amplifier circuit in probiotic E. coli to control the release of darobactin, a peptide antibiotic, at 40°C while maintaining low leakiness at 37°C.

Rheological behavior of Pluronic/Pluronic diacrylate hydrogels used for bacteria encapsulation

This study investigates the rheological properties of Pluronic/Pluronic diacrylate hydrogels with varying crosslinking fractions to correlate mechanical behavior with bacterial growth.

Plasmonic Stimulation of Gold Nanorods for the Photothermal Control of Engineered Living Materials

This paper demonstrates the use of plasmonic gold nanorods to control engineered living materials via infrared photothermal heating, enabling spatially controlled stimulation of thermoresponsive bacteria.

Light-regulated pro-angiogenic engineered living materials

This study develops light-controlled engineered living materials that release pro-angiogenic proteins, demonstrating their ability to bind collagen and promote angiogenesis in human endothelial cells.

Optical Metabolic Imaging Uncovers Sex- and Diet-dependent Lipid Changes in Aging Drosophila Brain

This study uses optical metabolic imaging to show diet and sex influence lipid metabolism in aging Drosophila brains, revealing IIS pathway involvement.

Encapsulation of bacteria in bilayer Pluronic thin film hydrogels: a safe format for engineered living materials

This study develops a bilayer hydrogel that encapsulates genetically engineered bacteria, enabling long-term viability and controlled release for engineered living materials.

In vitro evaluation of immune responses to bacterial hydrogels for the development of living therapeutic materials

This study evaluates immune responses to bacterial hydrogels, showing encapsulation reduces immunogenicity and apoptosis, making them suitable for living therapeutic materials.

Benzopyrene biodegradation by multiple and individual mesophilic bacteria in axenic conditions and in soil samples

The paper isolates three bacterial strains capable of degrading benzo[a]pyrene and evaluates their individual and consortium growth and degradation rates under controlled conditions.

Regulating bacterial behavior within hydrogels of tunable viscoelasticity

This study shows how bacterial behavior in hydrogels can be controlled by adjusting the mechanical properties of the matrix, with implications for designing engineered living materials.

Exogenous supply of Hsp47 triggers fibrillar collagen deposition in skin cell cultures in vitro

This study shows that adding Hsp47 to skin cell cultures increases fibrillar collagen deposition, with varying effects across different cell types.

Clustering and correlations: Inferring resilience from spatial patterns in ecosystems

This paper examines the relationship between spatial clustering patterns and ecosystem resilience, finding that power-law clustering does not reliably indicate ecosystem thresholds or collapse.