Author

S. Vincoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

A. H. Desphande· 1 shared A. J. Armstrong· 1 shared B. Schleupner· 1 shared D. Srijay· 1 shared J. Mao· 1 shared J. Santos· 1 shared J. Somarelli· 1 shared K. Kholina· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. H. Desphande

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Author profile →

2 papers

Recent·Most cited

Toxicogenomic analysis of the carcinogenic potential of plastic additives

S. Vincoff, B. Schleupner, J. Santos, M. Morrison, N. Zhang, M. M. Dunphy-Daly, W. C. Eward, A. J. Armstrong, Z. Diana, J. Somarelli

This study analyzes the carcinogenic potential of 2,712 plastic additives using toxicogenomic methods, finding over 150 known carcinogens and most lacking carcinogenicity data.

bioRxiv · Jun 30, 2023 · PreprintPharmacology & Toxicology

De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling

S. Bhat, K. Palepu, L. Hong, J. Mao, T. Ye, R. Iyer, L. Zhao, T. Chen, S. Vincoff, R. Watson, T. Wang, D. Srijay, V. S. Kavirayuni, K. Kholina, S. Goel, , P. Chatterjee

This paper designs short, target-binding linear peptides using a contrastive learning framework, demonstrating effective binding and degradation of conformationally diverse proteins.

bioRxiv · Jun 26, 2023 · PreprintBioengineering