Author

T. Ran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Zhou· 1 shared B. Xue· 1 shared C. Huan· 1 shared D. Guo· 1 shared G. Zhang· 1 shared H. Chen· 1 shared H. Wang· 1 shared J. Chen· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Zhou

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Discovery of orally bioavailable SARS-CoV-2 papain-like protease inhibitor as a potential treatment for COVID-19

Y. Lu, Q. Yang, T. Ran, G. Zhang, W. Li, P. Zhou, J. Tang, M. Dai, J. Zhong, H. Chen, P. He, A. Zhou, B. Xue, J. Chen, J. Zhang, , J. Shang

The paper identifies a potent orally bioavailable SARS-CoV-2 PLpro inhibitor with in vitro and in vivo antiviral activity against SARS-CoV-2 and related coronaviruses.

bioRxiv · Apr 3, 2024Microbiology

Physiology and structure of pathogenic Escherichia coli pOmpT reveal two substrate-binding sites

J. Liu, T. Ran, L. Jiang, Q. Gao, C. Huan, H. Wang, W. Wang, S. Gao, X. Liu

The paper identifies two substrate-binding sites in pOmpT that enable specific cleavage of human AMP RNase 7, revealing structural basis for substrate specificity and drug development clues.

bioRxiv · Jun 17, 2022 · PreprintMicrobiology