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The paper quantifies intraROS and apoROS accumulation in wheat infected by Bgt, showing that intraROS contributes to localized cell death in NLR R gene lines, while unconventional R genes show reduced intraROS responses.

This study identifies activin A's role in bone fracture repair by promoting a novel myofibroblastic progenitor cell population that drives chondrogenesis and osteogenesis.

This study shows that iron chelation with deferiprone improves ineffective erythropoiesis and iron overload in MDS mice by normalizing iron metabolism and reducing oxidative stress.

This paper uses airborne imaging spectroscopy and machine learning to detect GLRaV-3 infection in grapevines during the latent, asymptomatic phase, achieving high accuracy at 3-meter resolution.

This study shows that circadian genes are dysregulated in ASD patients' lymphoblastoid cells, linked to sleep phenotypes and altered gene networks.

This study shows that PKR inhibition reduces mitochondrial dysfunction and ameliorates HIV-associated nephropathy in transgenic mice using single-nucleus and bulk RNA-seq.

This study shows S100A4 promotes smooth muscle cell motility in vitro but does not affect intimal thickening formation in a mouse carotid artery ligation model.

This study uses spatial transcriptomics to analyze SARS-CoV-2 infection in coronary endothelial and myocardial tissues from COVID-19 patients, finding unique pro-inflammatory profiles in capillaries but not larger vessels.

This paper develops a multi-model platform to study atrial fibrillation-associated genes, identifying phospholamban as a key regulator of cardiac rhythm through interactions with calcium handling proteins.

This study uses interpretable deep learning to identify myelin pallor in brain tissue associated with cognitive impairment from postmortem human samples.

The paper analyzes HER2-positive breast cancer tumors at the single-cell level to identify phenotypic heterogeneity and its implications for response to HER2-targeted therapies.

The paper develops a single-cell MRD assay that detects residual leukemic clones with high sensitivity and reveals clonal architecture in AML.

This study shows that FGF21 overexpression in the liver reduces lipotoxicity, inflammation, and fibrosis in NASH by blocking lipid influx and macrophage activation.

This study compares dimethyl fumarate (DMF) and prednisone (PRED) in mdx mice, finding DMF improves muscle function and mitochondrial health while PRED causes side effects.

This study identifies VCAM-1 upregulation as a key marker of AKI-to-CKD transition, distinct from KIM-1, through mouse models and human single-cell transcriptomics.

This study investigates pulmonary lesions in rats exposed to titanium dioxide nanoparticles, identifying a new lesion type called pulmonary dust foci associated with pneumoconiosis-like effects.

The paper investigates the pathology of African swine fever in naturally infected wild boar, finding that variant IV causes a protracted disease course with lower viral load but more chronic lesions.

This study shows that PRR antagonism reduces hepatic steatosis and fibrosis in NAFLD models without affecting body weight or glucose levels.

This study examines how serum from chronic heat-not-burn cigarette smokers affects cardiac stromal cells, showing increased fibrosis and reduced paracrine support.

This study investigates the effect of titanium dioxide application on Fusarium wilt incidence, severity, and tomato yield in three tomato accessions, finding that 1.3 ml/l TiO2 significantly reduces disease and improves yield.