Author

K. Capistrano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Do· 3 shared M. Li· 3 shared A. Hakimi· 2 shared B. Nixon· 2 shared C. Chou· 2 shared E. Stamatiades· 2 shared F. Kuo· 2 shared J. Hsieh· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. Do

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Glycolysis Fuels Phosphoinositide 3-Kinase Signaling to Bolster T Cell Immunity

K. Xu, N. Yin, M. Peng, E. Stamatiades, A. Shyu, P. Li, X. Zhang, M. Do, Z. Wang, K. Capistrano, C. Chou, A. Levine, A. Rudensky, M. Li

This study shows that glycolysis fuels PI3K signaling in CD8+ T cells, linking metabolic reprogramming to T cell immunity and suggesting therapeutic targets for infectious diseases and cancer.

Science · Jan 22, 2021Peer-reviewedImmunology

IRF8 Governs Tumor-Associated Macrophage Control of T Cell Exhaustion

B. Nixon, F. Kuo, M. Liu, K. Capistrano, M. Do, R. Franklin, X. Wu, E. Kansler, R. Srivastava, T. Purohit, A. Sanchez, L. Vuong, C. Krishna, H. Morse, J. Hsieh, , M. Li

This study identifies IRF8 as a key factor in tumor-associated macrophages (TAMs) that induce T cell exhaustion by presenting cancer antigens, and shows its association with poor patient survival in renal cell carcinoma.

bioRxiv · Mar 12, 2020 · PreprintImmunology

TGFβ Suppresses Type 2 Immunity to Cancer

M. Liu, F. Kuo, K. Capistrano, D. Kang, B. Nixon, W. Shi, C. Chou, M. Do, S. Li, E. Stamatiades, Y. Chen, J. Hsieh, A. Hakimi, I. Taniuchi, T. Chan, M. Li

This study shows that blocking TGFβ signaling in CD4+ T cells enhances type 2 immunity, promoting tumor healing and halting cancer progression through IL-4-mediated vasculature repair.

bioRxiv · Mar 4, 2020 · PreprintImmunology