Author

F. Kuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

T. Chan· 3 shared A. Hakimi· 2 shared B. Nixon· 2 shared J. Hsieh· 2 shared K. Capistrano· 2 shared M. Do· 2 shared M. Li· 2 shared M. Liu· 2 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

T. Chan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Multimodal Atlas of Tumor Metabolism Reveals the Architecture of Gene-Metabolite Co-regulation

E. Benedetti, E. M. Liu, C. Tang, F. Kuo, M. Buyukozkan, T. Park, J. Park, F. Correa, A. A. Hakimi, A. M. Intlekofer, J. Krumsiek, E. Reznik

The paper constructs a multimodal tumor metabolism atlas to identify gene-metabolite co-regulation patterns across cancer types.

bioRxiv · Nov 23, 2022 · PreprintCancer Biology

IRF8 Governs Tumor-Associated Macrophage Control of T Cell Exhaustion

B. Nixon, F. Kuo, M. Liu, K. Capistrano, M. Do, R. Franklin, X. Wu, E. Kansler, R. Srivastava, T. Purohit, A. Sanchez, L. Vuong, C. Krishna, H. Morse, J. Hsieh, , M. Li

This study identifies IRF8 as a key factor in tumor-associated macrophages (TAMs) that induce T cell exhaustion by presenting cancer antigens, and shows its association with poor patient survival in renal cell carcinoma.

bioRxiv · Mar 12, 2020 · PreprintImmunology

TGFβ Suppresses Type 2 Immunity to Cancer

M. Liu, F. Kuo, K. Capistrano, D. Kang, B. Nixon, W. Shi, C. Chou, M. Do, S. Li, E. Stamatiades, Y. Chen, J. Hsieh, A. Hakimi, I. Taniuchi, T. Chan, M. Li

This study shows that blocking TGFβ signaling in CD4+ T cells enhances type 2 immunity, promoting tumor healing and halting cancer progression through IL-4-mediated vasculature repair.

bioRxiv · Mar 4, 2020 · PreprintImmunology

Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions

M. Dalin, N. Katabi, M. Persson, K.-W. Lee, V. Makarov, A. Desrichard, L. Walsh, L. West, Z. Nadeem, D. Ramaswami, J. Havel, F. Kuo, K. Chadalavada, G. Nanjangud, N. Riaz, , L. G. T. Morris

This study identifies prevalent oncogenic gene fusions in myoepithelial carcinoma through genomic analysis, highlighting TGFBR3-PLAG1 as a key fusion and potential therapeutic target.

bioRxiv · Jun 9, 2017Cancer Biology